# RETRACTED: Tiny bryophytes: nature's hidden reservoirs of powerful anti-cancer compounds

**Authors:** Ruturaj S Shete, Maruti J Dhanavade, Mudasir A Dar, Shashikant J Chavan

PMC · DOI: 10.1093/plcell/koaf268 · The Plant Cell · 2025-11-05

## TL;DR

Tiny bryophytes contain powerful anti-cancer compounds that could serve as natural alternatives to traditional cancer drugs.

## Contribution

The paper identifies and highlights potent anticancer compounds from bryophytes with proven efficacy against cancer cell lines.

## Key findings

- Marchantin A, phytol, and perrottetin E show significant efficacy in inhibiting cancer cell lines.
- Prenylated bibenzyls and phenanthrene demonstrate potential as anticancer agents.
- Bryophytes are a promising natural source of less toxic anticancer compounds.

## Abstract

Bryophytes are a promising source of bioactive compounds, offering a natural alternative to conventional anticancer drugs known for their cytotoxicity. This article highlights potent anticancer agents such as Marchantin A, phytol, perrottetin E, phenanthrene, and prenylated bibenzyls, which have demonstrated significant efficacy in inhibiting and destroying various cancer cell lines.

## Linked entities

- **Chemicals:** Marchantin A (PubChem CID 442710), phytol (PubChem CID 5280435), perrottetin E (PubChem CID 10646095), phenanthrene (PubChem CID 995)
- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** cytotoxicity (MESH:D064420), Cancer (MESH:D009369)
- **Chemicals:** Marchantin A (MESH:C096123), Perrottetin E (-), Phenanthrene (MESH:C031181), Phytol (MESH:D010836)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12771514/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12771514/full.md

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Source: https://tomesphere.com/paper/PMC12771514