# Viral proteins as discovery tools for cell biology: The case of the geminivirus-encoded C4 **Authors:** Shaojun Pan, Hua Wei, Frederik Dröst, Amit Fenn, Nadia Kamal, Rosa Lozano-Durán PMC · DOI: 10.1371/journal.ppat.1013798 · PLOS Pathogens · 2026-01-05 ## Full-text entities - **Genes:** C4 protein [NCBI Gene 949140], CDKN2D (cyclin dependent kinase inhibitor 2D) [NCBI Gene 1032] {aka INK4D, p19, p19-INK4D}, CASR (calcium sensing receptor) [NCBI Gene 846] {aka CAR, EIG8, FHH, FIH, GPRC2A, HHC}, BCAR1 (BCAR1 scaffold protein, Cas family member) [NCBI Gene 9564] {aka CAS, CAS1, CASS1, CRKAS, P130Cas}, RCC1 (regulator of chromosome condensation 1) [NCBI Gene 1104] {aka CHC1, IIAAN, RCC1-I}, CaS (calcium sensing receptor) [NCBI Gene 832370] {aka MYJ24.5, MYJ24_5, calcium sensing receptor} - **Diseases:** infection (MESH:D007239), viral infection (MESH:D014777) - **Chemicals:** SA (MESH:D020156) - **Species:** Zea mays (maize, species) [taxon 4577], Tomato yellow leaf curl virus (no rank) [taxon 10832], Homo sapiens (human, species) [taxon 9606], Pseudomonas syringae pv. actinidiae (no rank) [taxon 103796], Tomato leaf curl Guangdong virus (no rank) [taxon 400835], Pseudomonas syringae pv. tomato (no rank) [taxon 323], Beta vulgaris (beet, species) [taxon 161934], Solanum lycopersicum (tomato, species) [taxon 4081], Manihot esculenta (cassava, species) [taxon 3983], Phaseolus vulgaris (common bean, species) [taxon 3885], Arabidopsis thaliana (mouse-ear cress, species) [taxon 3702], Hordeum vulgare (barley, species) [taxon 4513], Mungbean yellow mosaic virus (no rank) [taxon 33726], Tobacco mosaic virus (no rank) [taxon 12242], Triticum aestivum (bread wheat, species) [taxon 4565], Sclerotinia sclerotiorum (species) [taxon 5180], Pseudomonas syringae (species) [taxon 317], Tomato bushy stunt virus (no rank) [taxon 12145], Lotus japonicus (species) [taxon 34305], Nicotiana benthamiana (species) [taxon 4100] ## Full text _Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12768228/full.md ## Figures 2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12768228/full.md ## References 23 references — full list in the complete paper: https://tomesphere.com/paper/PMC12768228/full.md --- Source: https://tomesphere.com/paper/PMC12768228