# Informal over-the-counter supply of antibiotics in Ghana: A qualitative analysis of practices in community pharmacies

**Authors:** Radolf Ansbert Nortey, Irene Akwo Kretchy, Mercy Naa Aduele Opare-Addo

PMC · DOI: 10.1016/j.rcsop.2025.100696 · Exploratory Research in Clinical and Social Pharmacy · 2025-12-10

## TL;DR

This study explores why antibiotics are sold without prescriptions in Ghanaian pharmacies, highlighting factors like economic incentives and weak regulations.

## Contribution

The study identifies socio-economic and community-specific factors influencing antibiotic over-the-counter supply in Ghana.

## Key findings

- Pharmacy practitioners supply antibiotics without prescriptions due to economic incentives and customer pressure.
- Urban pharmacies are more likely to provide antibiotics without prescriptions than rural ones.
- Pharmacy staff lack awareness of national antimicrobial policies.

## Abstract

Antibiotics are among the most widely prescribed medicines and fall within a well-defined framework for access and supply. Despite existing regulatory systems for antibiotic control, weak regulatory enforcement has led to non-prescription access from community drug retail outlets and widespread self-medication with antibiotics.

To explore the factors associated with the over-the-counter supply of antibiotics within community pharmacies across Ghana.

The exploratory qualitative study employed semi-structured interviews. The study population consisted of pharmacy practitioners randomly recruited from the medicine retail outlets situated in rural, peri-urban, and urban communities in Ghana. The interview questions were organised within the framework of the theory of planned behaviour and investigated participants' attitudes, social norms, and perceived control over antibiotic use. The data was transcribed, coded, and thematically analysed using NVivo version 10.

Twenty-three pharmacy practitioners (i.e., pharmacists, pharmacy technicians, and medicine counter assistants) participated in the study. Participants described how economic incentives, sales targets, and the perceived social status of customers often pressured them to supply antibiotics without prescriptions, especially in an environment where regulatory oversight was viewed as weak or absent. Many noted that customers felt increasingly entitled to request antibiotics, drawing confidence from online health information and limited public education. Although the participants knew about antibiotics and antimicrobial resistance, their awareness of existing national antimicrobial policies was limited.

The over-the-counter supply of antibiotics in Ghana is fuelled by various factors that differ slightly along the lines of community urbanisation and development. Policy makers must take full cognisance of these factors and adopt community-tailored strategies that target medicine retailers.

•Non-prescription supply of antibiotics is influenced by various socio-economic factors•It is more likely to meet pharmacists in pharmacies within urban areas than pharmacies in rural zones.•Pharmacy practitioners are unaware about existing antimicrobial policies.•Policy actors need to develop a guidance framework for pharmacists to streamline the supply of antibiotics.

Non-prescription supply of antibiotics is influenced by various socio-economic factors

It is more likely to meet pharmacists in pharmacies within urban areas than pharmacies in rural zones.

Pharmacy practitioners are unaware about existing antimicrobial policies.

Policy actors need to develop a guidance framework for pharmacists to streamline the supply of antibiotics.

## Full-text entities

- **Diseases:** OTCMS (MESH:D006963), shock (MESH:D012769), AMR (MESH:D060467), anxiety (MESH:D001007), infectious diseases (MESH:D003141), COVID-19 (MESH:D000086382)
- **Chemicals:** Artemether (MESH:D000077549), azithromycin (MESH:D017963), Augmentin (MESH:D019980), Aziromyses (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

69 references — full list in the complete paper: https://tomesphere.com/paper/PMC12767788/full.md

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Source: https://tomesphere.com/paper/PMC12767788