# Bee Venom Acupuncture in the Treatment of Musculoskeletal System Disorders: A Comprehensive Review

**Authors:** Xiaodi Zou, Yanzhao Dong, Ahmad Alhaskawi, Haiying Zhou, Sohaib Hasan Abdullah Ezzi, Vishnu Goutham Kota, Mohamed Hasan Abdulla Hasan Abdulla, Sahar Ahmed Abdalbary, Zhenfeng Liu, Changxin Wang, Hui Lu

PMC · DOI: 10.1155/prm/1766393 · Pain Research & Management · 2025-12-26

## TL;DR

This paper reviews bee venom acupuncture's use in treating musculoskeletal disorders, focusing on its healing effects and safety.

## Contribution

The paper provides a comprehensive review of bee venom acupuncture's therapeutic potential and mechanisms for musculoskeletal conditions.

## Key findings

- Bee venom acupuncture is traditionally used in Asian countries for musculoskeletal disorders.
- Melittin, a key component of bee venom, is central to its therapeutic effects.
- The review examines the healing capabilities and safety of bee venom acupuncture.

## Abstract

Disorders of the musculoskeletal system cover a broad spectrum of conditions that impact the muscles, skeletal structure, joints, tendons, and ligaments, leading to discomfort, swelling, and limited movement. Bee venom acupuncture (BVA), a practice commonly used in Asian countries, has been employed for a considerable time in traditional medicine systems to treat these disorders by utilizing bee venom and its main constituent, melittin. The purpose of this extensive evaluation on is to offer a detailed examination of the healing capabilities, modes of operation medical uses, and safety records of melittin and BVA in the treatment of different musculoskeletal disorders.

## Full-text entities

- **Diseases:** swelling (MESH:D004487), musculoskeletal disorders (MESH:D009140), Disorders of the musculoskeletal system (MESH:D009139)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12767433/full.md

## References

62 references — full list in the complete paper: https://tomesphere.com/paper/PMC12767433/full.md

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Source: https://tomesphere.com/paper/PMC12767433