# Bibliometric Analysis of Apoptotic Vesicles for Tissue Regeneration Research: Trends and Insights From 1991 to 2023

## TL;DR

This paper analyzes global research trends on apoptotic vesicles for tissue regeneration from 1991 to 2023, highlighting growth, key contributors, and future research directions.

## Contribution

A comprehensive bibliometric analysis of ApoVs in tissue regeneration, revealing collaboration patterns and emerging research hotspots.

## Key findings

- Global publications on ApoVs for tissue regeneration have steadily increased over the past 30 years.
- The United States leads in research output and citations, with the University of Tehran Medical Sciences being the most prolific institution.
- Subtopics like regenerative medicine and mesenchymal stem cells are emerging as key research areas.

## Abstract

Apoptotic vesicles (ApoVs) have garnered considerable attention within the realm of tissue regeneration research, necessitating a comprehensive bibliometric analysis to delineate current international trends and to map out historical and contemporary developments in this domain.

This study conducted a bibliometric analysis leveraging data sourced from the SCI‐Expanded Web of Science (WOS) database. The analysis encompassed publications from October 1, 1991, to December 31, 2023. A total of 1209 articles focusing on ApoVs for tissue regeneration were scrutinized, considering attributes such as publication year, journal, author, institution, country/region, references, and keywords. Coauthorship, cocitation, co‐occurrence analyses, network visualizations were generated using VOSviewer and CiteSpace.

The analysis indicated a steady annual rise in global publications pertaining to ApoVs for tissue regeneration. The United States emerged as the foremost contributor, with the highest citation count and H‐index. Furthermore, University of Tehran Medical Sciences was pinpointed as the most prolific institution. The journal International Journal of Molecular Sciences issued the largest account of articles on this topic. Notable subtopics such as “regenerative medicine,” “delivery,” and “mesenchymal stem cells” are poised to become significant research focal points in the near future.

Over the past 30 years, research on ApoVs for tissue regeneration has witnessed substantial growth, mirroring increasing collaboration across various countries and institutions. This study illuminates trends, collaboration patterns, research hotspots, and future trajectories in the field, providing valuable insights for researchers and practitioners.