# From overlooked to just right: putting the focus on metronidazole infusion timing for colorectal surgical prophylaxis

## TL;DR

This paper shows how adjusting the timing of metronidazole administration improved infection prevention in colorectal surgery.

## Contribution

A multidisciplinary approach standardized metronidazole infusion timing, leading to better surgical site infection outcomes.

## Key findings

- Standardizing metronidazole infusion timing increased completion rates before surgery.
- The intervention reduced surgical site infection rates in colorectal surgery patients.

## Abstract

Preoperative prophylaxis efficacy depends on antibiotic infusion completion before incision. In our colorectal program, metronidazole often wasn’t completed on time, in contrast to cefazolin. A multidisciplinary effort standardized its administration timing, improving infusion completion rates. We evaluated the impact of this intervention on surgical site infections in colorectal surgery.