# Synthesis and applications of alkenyl chlorides (vinyl chlorides): a review

## TL;DR

This paper reviews the synthesis and uses of alkenyl chlorides, highlighting their growing importance in organic chemistry.

## Contribution

The paper offers a comprehensive synthesis and application overview of alkenyl chlorides, emphasizing recent advances.

## Key findings

- Alkenyl chlorides have unique reactivity and utility in organic synthesis.
- Recent developments highlight their versatility as functional groups.
- The review organizes historical and modern methods for their synthesis.

## Abstract

Alkenyl chlorides constitute a synthetically valuable yet historically underexplored class of organohalides. First prepared in 1868 by Charles Friedel – best known for the Friedel–Crafts reaction – via the reaction of ketones with phosphorus pentachloride, these compounds have steadily gained attention over the decades. In recent years, their distinct reactivity and potential in organic synthesis have been increasingly recognized. This review provides a comprehensive overview of the synthesis and application of alkenyl chlorides, with a focus on developments over the past four decades. By organizing this growing body of work, I aim to highlight key advances and help guide the design of new transformations involving this important and versatile functional group.