# Case Report of Melody Valve Placement to Treat Neoaortic Valve Stenosis in an Adult With Fontan Circulation

**Authors:** Matthew C. Schwartz, Jorge Alegria, Jonathan Schwartz, Joseph Paolillo

PMC · DOI: 10.1016/j.jscai.2025.104018 · 2025-11-18

## TL;DR

A 31-year-old adult with a rare heart condition successfully had a Melody valve placed to treat severe valve narrowing.

## Contribution

This case report is the second documented use of the Melody valve in the neoaortic position for hypoplastic left heart syndrome.

## Key findings

- Melody valve placement successfully treated neoaortic valve stenosis in a patient with hypoplastic left heart syndrome.
- The procedure was performed percutaneously, avoiding open-heart surgery.
- The patient showed improvement without major complications.

## Abstract

The Melody valve (Medtronic) is commonly used for pulmonary valve replacement in patients with dysfunctional right ventricle to pulmonary artery conduits or bioprosthetic pulmonary valves. Rare reports exist of its use in the aortic position, including only 1 prior description of its use in a patient with hypoplastic left heart syndrome. We describe a 31-year-old patient with hypoplastic left heart syndrome who had severe neoaortic valve stenosis and moderate regurgitation that was successfully treated with percutaneous Melody valve placement in the neoaortic position.

## Linked entities

- **Diseases:** hypoplastic left heart syndrome (MONDO:0004933)

## Full-text entities

- **Diseases:** hypoplastic left heart syndrome (MESH:D018636), Neoaortic Valve Stenosis (MESH:D001024), regurgitation (MESH:D008944)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12766046/full.md

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Source: https://tomesphere.com/paper/PMC12766046