Epilepsy-Induced Neurodegeneration and Its Therapeutic Interventions
Samar Kaddoura, Anjali Banerjee, Latha Ganti
TL;DR
This paper analyzes research trends on epilepsy-related brain damage and potential treatments to prevent or reverse it.
Contribution
The study provides a bibliometric analysis of epilepsy-induced neurodegeneration and therapeutic interventions.
Findings
662 publications on epilepsy-induced neurodegeneration were identified from 1989 to 2025.
Key terms include seizures, hippocampus, epileptogenesis, and oxidative stress.
Recent research shows promise for therapies to prevent or reverse neuronal damage in epilepsy.
Abstract
Epilepsy is a disease that is recognized not only as a disorder of recurrent seizures but also for its association with neurodegeneration. This bibliometric analysis aims to assess the scientific outputs, trends, and key contributors to epilepsy-induced degeneration and the treatments aimed at intervening in neuronal damage. The Web of Science yielded a total of 662 publications between 1989 and 2025. The analysis identifies many key terms associated with epilepsy and neurodegeneration, including seizures, hippocampus, epileptogenesis, and oxidative stress. With the rise in research on this topic in recent years, there is growing potential for developing therapies that may prevent or reverse neurodegeneration in patients with epilepsy.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsEpilepsy research and treatment · Pharmacological Effects and Toxicity Studies · Diet and metabolism studies