Solitary Bone Plasmacytoma of the Scapula: A Rare Localization With Remarkable Radiotherapy Outcome
Reyzane El Mjabber, Rim Alami, Ech-Cherki El Mjabber, Zineb Dahbi, Fadila Kouhen, Nabil Ismaili, Sanaa El Majjaoui, Asmaa Naim
TL;DR
A rare case of solitary bone plasmacytoma in the scapula showed excellent response to radiotherapy, highlighting its effectiveness for localized treatment.
Contribution
This case report documents a rare scapular localization of solitary bone plasmacytoma and its successful management with radiotherapy.
Findings
The patient showed significant lesion regression and partial re-ossification after 50 Gy radiotherapy.
Radiotherapy was well tolerated with minimal side effects (grade I radiodermatitis).
Long-term monitoring is emphasized due to the risk of progression to multiple myeloma.
Abstract
Solitary bone plasmacytoma (SBP) is a rare plasma cell neoplasm characterized by localized proliferation of monoclonal plasma cells in bone without systemic involvement, which distinguishes it from multiple myeloma. Although the axial skeleton is most frequently affected, involvement of the shoulder girdle is exceptionally uncommon. We present the case of a 48-year-old woman who experienced progressive left shoulder pain and noted an enlarging mass over six months. Imaging revealed a large osteolytic lesion in the scapula with extension into surrounding soft tissue. Histopathology and immunohistochemistry confirmed the diagnosis of solitary plasmacytoma. Comprehensive staging, including bone marrow biopsy and 18F-FDG PET/CT (Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography), excluded systemic disease. The patient underwent definitive radiotherapy,…
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Taxonomy
TopicsMultiple Myeloma Research and Treatments · Management of metastatic bone disease · Bone Tumor Diagnosis and Treatments