# From Behavior to the Built Environment: The Role of the Exposome on Cognitive Health

## TL;DR

This paper explores how the exposome, including social and physical environments, affects cognitive health across different life stages and diverse populations.

## Contribution

The study introduces new insights into how psychosocial and environmental factors influence cognitive health using diverse, longitudinal data.

## Key findings

- Well-being factors like life satisfaction are linked to cognitive health in Mexican-origin adults.
- Social cohesion and loneliness affect cognitive function in Latino populations.
- Neighborhood characteristics influence midlife cognitive performance in adoption-twin studies.

## Abstract

The exposome – the psychological, social, lifestyle, and physical environments where people live, connect, and work – plays an important role in supporting cognitive health across the lifespan. However, we know little about the mechanisms linking psychosocial, lifestyle, and built environment factors to cognitive health, as well as roles of the exposome across socioculturally-diverse populations. This symposium showcases innovative research that fills these gaps by leveraging longitudinal study designs (up to 14 years), multimethod data (e.g., self-report, geographical linkages, cognitive batteries), lifespan perspectives (from adolescence through older adulthood), and socioculturally-diverse populations (including samples of Mexican-origin and Latino individuals, and an adoption/twin study). First, Dr. Emily Willroth uses data from a 14-year longitudinal study of Mexican-origin adults to examine how well-being (i.e., life satisfaction, optimism) is related to modifiable dementia risk factors and cognitive health. Second, Dr. Graciela Muniz Terrera uses longitudinal data from a Latino sample to demonstrate how social cohesion and loneliness are associated with cognitive function and trajectories. Third, Dr. Chandra Reynolds uses longitudinal data from an adoption-twin study to demonstrate the role of neighborhood Cognability on cognitive performance in midlife, while also considering demographic, developmental, and neighborhood covariates. Finally, Dr. Olivia Atherton uses geographical linkages to the Health and Retirement Study to characterize discrepancies between health behavior engagement and built environment opportunities, as well as the impact of behavior-opportunity gaps on cognitive health. We conclude with a general discussion of future directions in understanding the role of the exposome on cognitive health and healthy aging in place.

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Source: https://tomesphere.com/paper/PMC12763328