Could the Biological Potency of Porcelia macrocarpa R.E. Fries (Annonaceae) be Linked to Its Diverse Metabolite Profile?
Fernanda Thevenard, Ivanildo A. Brito, Emerson A. Oliveira, Mariana H. Chaves, João Henrique G. Lago
TL;DR
This paper reviews the diverse chemical compounds in Porcelia macrocarpa and their potential medical uses.
Contribution
The paper provides a comprehensive overview of P. macrocarpa's metabolites and their biological activities.
Findings
Over 190 compounds have been identified in Porcelia macrocarpa.
Terpenoids are the most abundant compound class in the plant.
The metabolites show a wide range of biological activities, including antibacterial and anti-inflammatory effects.
Abstract
Porcelia macrocarpa is a Brazilian plant species belonging to the Annonaceae family. To date, more than 190 compounds have been identified and/or isolated from this species, with terpenoids comprising the majority (62%). Alkaloids represent the second most abundant class (11%), followed by steroids (4%), acetogenins (4%), fatty acids (4%), arylpropanoids (3%), and flavonoids (1%). These metabolites exhibit a wide range of biological activities, including antibacterial, antifungal, antiviral, cytotoxic, anti‐inflammatory, antiparasitic, and antioxidant effects. This review highlights the remarkable chemical profile of P. macrocarpa and the pharmacological potential of the metabolites identified in this species, offering valuable insights into its possible applications and encouraging further research across multiple scientific and medical fields.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsTraditional and Medicinal Uses of Annonaceae · Ethnobotanical and Medicinal Plants Studies · Morinda citrifolia extract uses