# The Combined Association of Hearing Loss and Social Isolation on Dementia

## TL;DR

This study finds that both hearing loss and social isolation together are linked to a higher risk of dementia compared to either condition alone.

## Contribution

The study examines the combined effect of hearing loss and social isolation on dementia risk in older adults.

## Key findings

- The prevalence of dementia was 2.42 times higher in individuals with both hearing loss and social isolation.
- Hearing loss alone was associated with a 1.95 times higher dementia risk compared to those without either condition.
- No statistically significant interaction was found between hearing loss and social isolation in dementia risk.

## Abstract

Hearing loss (HL) and social isolation (SI) are considered independent, modifiable risk factors for dementia. However, the modifying role of SI in the HL–dementia relationship remains unclear. We conducted a cross-sectional analysis of community-dwelling adults aged ≥65 in the U.S. from the nationally representative 2022 National Health and Aging Trends Study (NHATS) (n = 4,712). HL was defined as a better-ear pure tone average >25 decibels using a tablet-based auditory assessment. We measured binary SI using a four-domain typology (living arrangement, core discussion network, religious services attendance, and social participation). Dementia was evaluated using the NHATS dementia algorithm (reported dementia diagnosis, AD8, and neurocognitive tests). We used survey-weighted Poisson regressions to test if the additional presence of SI among older adults with hearing loss was associated with a higher risk of dementia. The prevalence of HL, SI, both combined and dementia, were 56.0%, 21.9%, 14.4%, and 9.2%, respectively. Compared to those without HL or SI, the prevalence ratio for dementia was 1.95 (95% CI: 1.38, 2.75) for HL alone, and 1.30 (95% CI: 0.75, 2.25) for SI alone, and 2.42 (95% CI: 1.66, 3.52) for those with both conditions. The super-additive interaction between HL and SI was not statistically significant (Synergy Index = 1.1, 95% CI: 0.4, 1.9). These findings suggest the presence of both HL and SI is associated with a higher prevalence of dementia compared to either factor alone. While no significant interaction was observed, HL management should consider coexisting isolation for dementia prevention.