# A Latent Class Analysis of Health Characteristics Among Non-Drinking Middle-Aged and Older Adults

**Authors:** Sara Miller, Jennifer Maggs, Stephanie Lanza

PMC · DOI: 10.1093/geroni/igaf122.2510 · Innovation in Aging · 2025-12-31

## TL;DR

This study identifies five distinct health profiles among non-drinking middle-aged and older adults in the U.S.

## Contribution

The paper introduces a novel latent class analysis of non-drinkers' health characteristics to better understand health variability in this population.

## Key findings

- Five distinct health profiles were identified among non-drinking adults aged 50+.
- Age, education, and biological sex predicted class membership, but not alcohol use history.
- The largest group (38%) had good overall health, while 5.9% had poor overall health.

## Abstract

Despite documented health consequences of heavy alcohol consumption, there is ongoing debate around potential health benefits of low-to-moderate alcohol use. Better understanding variability in health characteristics among non-drinkers can inform discourse around the alcohol j-curve and underscore the diverse health profiles of adults who abstain in later life. The current study aimed to identify latent classes of non-drinkers based on subjective and objective health characteristics and examine person-level predictors of class membership. Participants were adults aged 50+ years in the Midlife in the United States study who did not report past-month alcohol use (N = 1,205; range=50-84 years). Dichotomous health indicators included any functional impairment, obesity, cardiometabolic risk factors (diabetes, high blood pressure, or stroke), chronic pain, chronic sleep problems, self-reported physical health (1=Fair/Poor; 2=Excellent/Very Good/Good), perceived health in comparison to others (1=Somewhat Worse/Much Worse, 2=Much Better/Somewhat Better/About the Same), chronic depression and/or anxiety, and self-reported mental health (1=Fair/Poor; 2=Excellent/Very Good/Good). Person-level predictors included age (1=Older Adult, 0=Middle-Aged), sex (1=Male, 0=Female), alcohol use history (1=Lifetime Abstainer, 0=Former Drinker), and education (1=College Degree or Higher, 0=Less Than College Degree). Five latent classes were identified: poor overall health (5.9%), poor physical and self-reported health but good mental health (17.9%), poor physical health but good self-reported and mental health (28.5%), good self-reported health but poor physical and mental health (9.8%), and good overall health (38.0%). Age, education, and biological sex, but not alcohol use history, predicted probability of class membership. Future research can explore how the underlying latent classes predict distal health outcomes.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015), high blood pressure (MONDO:0005044), stroke (MONDO:0005098), anxiety (MONDO:0005618)

---
Source: https://tomesphere.com/paper/PMC12760849