The Impact of Intrinsic Capacity on Quality of Life in Older Adults: A Multidimensional SEM Analysis
Zhen Wu, Lulu Xiao, Junyan Zeng, Ershuo Zhao, Haijun Zhao, Shixing Song, Yan Dong, Linlin Hu

TL;DR
This study explores how older adults' intrinsic capacity affects their quality of life through factors like frailty, pain, and anxiety, showing that social support and comorbidity play key roles.
Contribution
The study empirically validates the WHO Intrinsic Capacity framework by quantifying its clinical-social pathways in older adults.
Findings
Intrinsic Capacity (IC) indirectly influences quality of life through fall risk, frailty, ADL, pain, and anxiety.
Social support and caregiver availability moderate IC's effects, while comorbidity amplifies these pathways.
The WHO IC framework is validated as a multidimensional model for quality of life in aging populations.
Abstract
Amidst global population aging, while the WHO’s Intrinsic Capacity (IC) framework offers critical insights into multidimensional quality of life (QoL) determinants in older adults, systematic quantification of its clinical-social pathways remains limited. This cross-sectional study of 509 older adults (mean age 78.4±8.5 years) across community and institutional settings from China employed structural equation modeling with 5,000 bootstrap samples to examine pathways linking WHO-measured IC to EQ-5D-assessed QoL through frailty phenotype, Barthel Index (ADL), Visual Analog Scale (pain), Self-Rating Anxiety Scale, and Morse Fall Risk. The model demonstrated excellent fit (χ²/df=1.556, CFI=0.995, RMSEA=0.035). IC exhibited nonsignificant direct effects on QoL (β = 0.019, p = 0.416) versus robust indirect mediation through: Fall Risk (β = 0.090, 95%CI[0.065,0.120], 92.3% mediation),…
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsFrailty in Older Adults · Chronic Disease Management Strategies · Aging and Gerontology Research
