# A Rare Presentation of Babesia‐Associated Splenic Infarction in an Immunocompetent Young Male With Mild Parasitemia

**Authors:** Jamal A. Anthony, Dejan Nikolic, Rosalie Pepe, Henry Fraimow

PMC · DOI: 10.1155/carm/5210024 · Case Reports in Medicine · 2026-01-02

## TL;DR

A young, healthy man with mild babesiosis experienced a rare complication of splenic infarction, highlighting the disease's potential severity even with low parasite levels.

## Contribution

Reports a rare case of splenic infarction in a young, immunocompetent individual with mild babesiosis parasitemia.

## Key findings

- A young, immunocompetent male developed severe babesiosis with splenic infarction.
- The patient had low parasitemia levels, challenging the assumption that high levels are required for severe disease.
- The case highlights the need for awareness of rare complications in mild babesiosis cases.

## Abstract

Babesiosis is a vector‐borne protozoal disease primarily transmitted by the Ixodes scapularis tick, though it can also be transmitted through blood transfusions from infected donors. The illness can be asymptomatic or present with mild flu‐like symptoms. Still, in severe cases, it can lead to disseminated intravascular coagulation and severe hemolytic anemia, sometimes necessitating management in the intensive care unit. Traditionally, severe babesiosis has been linked to individuals over 50 years old, asplenia, and those who are immunocompromised. Notably, parasitemia levels greater than 10% are also associated with severe disease. However, we report a case of a young, immunocompetent male with severe babesiosis exhibiting severe hemolytic anemia and a rare complication of splenic infarction despite a low level of parasitemia. This case emphasizes that significant clinical complications, like spontaneous splenic infarction, can arise from low parasitemia levels, underscoring the need for heightened awareness of this potential outcome.

## Linked entities

- **Diseases:** babesiosis (MONDO:0005661), hemolytic anemia (MONDO:0003664), splenic infarction (MONDO:0006978)
- **Species:** Ixodes scapularis (taxon 6945)

## Full-text entities

- **Diseases:** Parasitemia (MESH:D018512), protozoal disease (MESH:D020808), hemolytic anemia (MESH:D000743), disseminated intravascular coagulation (MESH:D004211), Splenic Infarction (MESH:D013159), asplenia (MESH:D059446), flu (MESH:D007251), Babesia (MESH:D001404)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12759178/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12759178/full.md

## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12759178/full.md

---
Source: https://tomesphere.com/paper/PMC12759178