# From microscopes to maps: enabling a new era of open and reproducible data sharing in intravital imaging

**Authors:** Moritz Peiseler

PMC · DOI: 10.1038/s44318-025-00630-x · The EMBO Journal · 2025-11-20

## TL;DR

This paper introduces Immunemap, a public database of intravital imaging data, to help study how immune cells move and interact in different organs.

## Contribution

The novelty lies in demonstrating how Immunemap enables open and reproducible data sharing for immune cell motility research.

## Key findings

- Immunemap includes imaging data from 20 leading laboratories.
- The database facilitates analysis of immune cell behavior in response to stimuli.
- Pizzagalli and colleagues show proof-of-principle analyses using Immunemap data.

## Abstract

Understanding the motility of immune cells and their interactions with their environment in response to different stimuli and in various organs has been a key objective in immunology. In this issue of The EMBO Journal, Pizzagalli and colleagues present proof-of-principle analyses of immune cell motility using data from the curated and publicly-accessible intravital microscopy database “Immunemap”, which includes imaging data from 20 leading laboratories.

New research in The EMBO Journal shows how the publicly accessible database Immunemap can facilitate the study of immune cell motility.

## Full-text entities

- **Diseases:** inflammation (MESH:D007249), infections (MESH:D007239), tissue injury (MESH:D017695)
- **Species:** Mus musculus (house mouse, species) [taxon 10090]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12759062/full.md

## References

1 references — full list in the complete paper: https://tomesphere.com/paper/PMC12759062/full.md

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Source: https://tomesphere.com/paper/PMC12759062