# Motor Fiber Tract Changes Following iTBS Stimulation in a Basal Ganglia Stroke Patient: A Case Report

**Authors:** Lei Xi, Qian Liu, Yuzhe Zou, Xue Yang, Liqing Yao

PMC · DOI: 10.1002/ccr3.71728 · Clinical Case Reports · 2026-01-02

## TL;DR

This case report shows that cerebellar stimulation can improve brain connectivity and recovery in a stroke patient.

## Contribution

Demonstrates cerebellar iTBS promotes neuroplastic changes in a basal ganglia stroke patient.

## Key findings

- Enhanced corticospinal tract connectivity was observed after 2 weeks of iTBS.
- Contralateral compensatory fiber reorganization occurred in specific brain regions.
- iTBS improved motor, cognitive, and emotional functions in the patient.

## Abstract

This case report describes the application of intermittent theta‐burst stimulation (iTBS) targeting the cerebellum in a 46‐year‐old female patient with basal ganglia infarction. Following a 2‐week intervention, enhanced corticospinal tract connectivity and contralateral compensatory fiber reorganization in specific brain regions were observed. These findings suggest that cerebellar iTBS may promote neuroplastic reorganization after basal ganglia stroke, underscoring the important role of the cerebello‐cortical pathway in functional recovery.

Intermittent theta‐burst stimulation applied to the cerebellum can promote enhanced corticospinal tract connectivity and contralateral compensatory fiber reorganization in patients with basal ganglia stroke, thereby improving their motor, cognitive, and emotional functions.

## Linked entities

- **Diseases:** stroke (MONDO:0005098)

## Full-text entities

- **Diseases:** basal ganglia infarction (MESH:D007238), Stroke (MESH:D020521)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12758993/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12758993/full.md

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Source: https://tomesphere.com/paper/PMC12758993