# Miller Fisher Variant of Guillain-Barré Syndrome Presenting With Dysphagia and Ophthalmoplegia

## TL;DR

This paper describes a rare case of Miller Fisher Syndrome, a variant of Guillain-Barré syndrome, where the patient initially showed dysphagia and ophthalmoplegia.

## Contribution

The paper highlights an unusual presentation of Miller Fisher Syndrome with dysphagia and ophthalmoplegia as initial symptoms.

## Key findings

- The patient presented with dysphagia and ophthalmoplegia as initial symptoms of Miller Fisher Syndrome.
- Dysphagia in combination with ophthalmoplegia is a rare presentation of Miller Fisher Syndrome.
- The case adds to the limited number of reported cases showing dysphagia as an initial symptom.

## Abstract

Miller Fisher syndrome (MFS) is a rare variant of Guillain-Barré syndrome (GBS). It is characterized by a triad of ataxia, areflexia, and ophthalmoparesis. Akin to GBS, it is often triggered by a respiratory infection, causing immune cross-activation against pathogenic proteins and gangliosides. Symptoms typically occur in chronological progression, beginning with ophthalmoparesis, then ataxia, and finally areflexia. Our case is of a patient presenting with dysphagia and ophthalmoplegia as the initial manifestations. There currently exist only a limited number of reported cases of MFS presenting with dysphagia, which, along with ophthalmoplegia, areflexia, and ataxia, should raise suspicion for MFS.