# Periprosthetic Proximal Femoral Fractures: A Comprehensive Review of Epidemiology, Risk Factors, Classification and Management

**Authors:** Andrew Foster, Mohammad Waseem Beeharry

PMC · DOI: 10.7759/cureus.100589 · Cureus · 2026-01-01

## TL;DR

This paper reviews periprosthetic proximal femoral fractures after hip replacement, focusing on risk factors, classification, and treatment strategies.

## Contribution

The paper provides a comprehensive review of PPFFs, emphasizing recent innovations in surgical techniques and emerging technologies.

## Key findings

- PPFFs are linked to patient-related and implant-related risk factors like age, osteoporosis, and prosthesis design.
- The Vancouver classification system is central to guiding treatment decisions based on fracture location and implant stability.
- New surgical techniques and technologies like 3D printing and AI are improving treatment outcomes for PPFFs.

## Abstract

Periprosthetic proximal femoral fractures (PPFFs) represent an increasingly prevalent complication following hip arthroplasty, driven by global demographic shifts and rising arthroplasty rates. These fractures pose significant clinical and surgical challenges due to their association with implant instability, compromised bone quality, and increased patient morbidity and mortality. The Vancouver classification system remains the cornerstone for fracture classification and management decision-making, distinguishing fractures by location, implant stability, and bone stock quality.

This review outlines the epidemiology and risk factors associated with PPFFs, highlighting both patient-related factors, such as advanced age, female sex, osteoporosis, and comorbidities, and implant-related factors, including prosthesis type, fixation method, stem sizing, and surgical approach. Each fracture subtype within the Vancouver classification is discussed, with emphasis on appropriate surgical strategies ranging from conservative management to complex revision arthroplasty.

Recent innovations in surgical fixation, including angle-stable and double plating, offer improved biomechanical stability and enhanced union rates. Furthermore, advances in 3D printing and artificial intelligence hold promise for custom implant design and data-driven treatment planning. Novel techniques, such as transprosthetic drilling with internal cooling systems, may further address fixation challenges in complex cases.

As the burden of PPFFs continues to grow, a comprehensive understanding of risk stratification, evidence-based treatment, and emerging technologies is essential to improve outcomes and optimize healthcare resource utilization.

## Linked entities

- **Diseases:** osteoporosis (MONDO:0005298)

## Full-text entities

- **Diseases:** PPFFs (MESH:D057068), Proximal Femoral Fractures (MESH:D000092526), osteoporosis (MESH:D010024), fracture (MESH:D050723)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

41 references — full list in the complete paper: https://tomesphere.com/paper/PMC12757879/full.md

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Source: https://tomesphere.com/paper/PMC12757879