# Clinical efficacy of the laparoscopic modified Soave procedure for Hirschsprung's disease: a comparative retrospective cohort study

**Authors:** Chuncan Ma, Yong Li, Yalan Xia, Xintao Zhang, Qiongqian Xu, Xixi He, Dong Sun, Jichang Han, Xue Ren, Dongming Wang, Jian Wang, Aiwu Li

PMC · DOI: 10.3389/fped.2025.1700323 · Frontiers in Pediatrics · 2025-12-19

## TL;DR

This study compares two surgical techniques for Hirschsprung's disease, finding that the laparoscopic method offers faster recovery and fewer complications.

## Contribution

The study provides new comparative evidence on the clinical efficacy of the laparoscopic modified Soave procedure for Hirschsprung's disease.

## Key findings

- The laparoscopic group had shorter surgical time, faster gastrointestinal recovery, and shorter hospital stays.
- The laparoscopic group had lower complication rates and less postoperative abdominal distension.
- Despite greater intraoperative blood loss, the laparoscopic method showed better overall clinical outcomes.

## Abstract

Hirschsprung's disease (HSCR) is the second most common congenital gastrointestinal malformation, posing a significant health concern in pediatrics. The laparoscopic modified Soave procedure, a minimally invasive technique, has gained popularity due to its potential advantages. This study aimed to evaluate its clinical efficacy in comparison with the traditional transanal Soave procedure.

This comparative retrospective cohort study included children with HSCR treated at Qilu Hospital between January 2014 and January 2024. The patients were divided into the following two groups: the Laparoscopic group (those who underwent the laparoscopic modified Soave procedure) and the Transanal group (those who underwent the transanal Soave procedure). The assessed outcomes included postoperative recovery metrics, complication rates, and 1-year follow-up results.

In total, 96 patients were included in the study. Compared with the Transanal group, the Laparoscopic group demonstrated reduced surgical time, faster gastrointestinal recovery, and reduced hospital stay duration (P < 0.05). Intraoperative blood loss was greater in the Laparoscopic group (P < 0.05). Complication rates were lower in the Laparoscopic group (4.17%) than in the Transanal group (14.58%), although the difference was not statistically significant (P > 0.05). Notably, the incidence of postoperative abdominal distension was lower in the Laparoscopic group (P < 0.05), but no significant differences observed in multivariate analysis of postoperative outcomes (P < 0.05).

The laparoscopic modified Soave procedure demonstrated superior clinical efficacy compared to the transanal approach, offering faster recovery and a trend toward fewer complications. These findings support its wider adoption as a minimally invasive treatment option for HSCR.

## Linked entities

- **Diseases:** Hirschsprung's disease (MONDO:0018309), HSCR (MONDO:0018309)

## Full-text entities

- **Diseases:** HSCR (MESH:D006627), gastrointestinal malformation (MESH:D005767), blood loss (MESH:D016063), abdominal distension (MESH:D000007)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12757382/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12757382/full.md

## References

39 references — full list in the complete paper: https://tomesphere.com/paper/PMC12757382/full.md

---
Source: https://tomesphere.com/paper/PMC12757382