# Case Report: Masquerading doughnut: a case of misdiagnosed ileocecal tumor-induced intussusception

**Authors:** Chuchu Xu, Renjun Zhu, Qingfeng Dai, Guangen Xu, Guolin Zhang

PMC · DOI: 10.3389/fonc.2025.1716593 · Frontiers in Oncology · 2025-12-19

## TL;DR

A young man's abdominal pain led to a misdiagnosis of separate tumors, but surgery revealed a single cancer causing intussusception.

## Contribution

Highlights diagnostic challenges of intussusception and CRC coexistence in young adults.

## Key findings

- A 21-year-old's CT scan suggested separate lesions, but surgery revealed a single ileocecal adenocarcinoma.
- Imaging limitations were evident in mischaracterizing the tumor-induced intussusception as multiple pathologies.

## Abstract

Intussusception in adults is rare and is often associated with an underlying pathology such as tumors. Its coexistence with colorectal cancer (CRC) in young patients presents unique diagnostic challenges as imaging may suggest separate lesions rather than a single malignancy.

A 21-year-old man presented with worsening right upper and central abdominal pain. The contrast-enhanced abdominal CT suggested that the intussusception at the ileocecal region might be caused by a lipoma and revealed a separate mass in the transverse colon. Emergency laparoscopic exploration and subsequent open laparotomy confirmed a 4.0-cm × 5.0-cm cauliflower-like adenocarcinoma originating from the ileocecal region, which had caused the intussusception and mimicked separate pathologies on imaging.

This case highlights the diagnostic complexity of synchronous intestinal lesions in young patients. It underscores the need for a heightened suspicion of an underlying malignancy when encountering intussusception and emphasizes the limitations of imaging in accurately characterizing the complex pathology of the bowel.

## Linked entities

- **Diseases:** colorectal cancer (MONDO:0005575), intussusception (MONDO:0007835)

## Full-text entities

- **Diseases:** ileocecal tumor (MESH:D044504), abdominal pain (MESH:D015746), malignancy (MESH:D009369), Intussusception (MESH:D007443), adenocarcinoma (MESH:D000230), lipoma (MESH:D008067), CRC (MESH:D015179)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12757245/full.md

## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC12757245/full.md

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Source: https://tomesphere.com/paper/PMC12757245