# Systemic Infection of Pediatric Osteomyelitis: A Clinical Case in a Low-Income Country

**Authors:** Pramodani Arulkumar, Rucha Bhat, Sibana Gonzalez, Aarush R Patlola, Sorivel Sosa

PMC · DOI: 10.7759/cureus.98326 · Cureus · 2025-12-02

## TL;DR

A seven-year-old child in a low-income country was diagnosed with MRSA-related osteomyelitis and systemic symptoms, emphasizing the need for early diagnosis and treatment in such regions.

## Contribution

This case report highlights the challenges and management of MRSA-associated pediatric osteomyelitis in a low-income country setting.

## Key findings

- MRSA was identified as the causative agent of osteomyelitis in a seven-year-old child.
- Early imaging and microbial isolation were critical for diagnosis and treatment.
- The case underscores the importance of multidisciplinary care in managing complex pediatric infections.

## Abstract

Osteomyelitis is a severe bone infection that requires early diagnosis and targeted treatment, mainly in pediatric populations where clinical presentations can be complex and nonspecific. This case report presents a seven-year-old male from Los Ríos, Santo Domingo, Dominican Republic, diagnosed with methicillin-resistant Staphylococcus aureus (MRSA)-associated osteomyelitis. The child presented with systemic signs, including fever, vomiting, and abdominal pain, along with localized trauma, limb pain, and functional limitations. Clinical examination revealed hemodynamic instability and gastrointestinal involvement, while laboratory findings indicated infection and malnutrition. Imaging confirmed osteomyelitis in the left femur and periosteal injury in the right forearm. Blood and soft tissue cultures identified MRSA as the causative agent. This case highlights the importance of early imaging, microbial isolation, and a multidisciplinary approach in the management of pediatric osteomyelitis, such as intravenous antibiotics, monitoring, and long-term medications. It also underscores the need for increased awareness and diagnostic capabilities in developing countries to facilitate timely intervention and reduce long-term complications.

## Linked entities

- **Diseases:** osteomyelitis (MONDO:0005246), malnutrition (MONDO:0006873)

## Full-text entities

- **Diseases:** Infection (MESH:D007239), bone infection (MESH:D001847), pain (MESH:D010146), fever (MESH:D005334), malnutrition (MESH:D044342), trauma (MESH:D014947), gastrointestinal involvement (MESH:D005767), vomiting (MESH:D014839), periosteal injury (MESH:D010522), Osteomyelitis (MESH:D010019), instability (MESH:D043171), abdominal pain (MESH:D015746)
- **Chemicals:** methicillin (MESH:D008712)
- **Species:** Staphylococcus aureus (species) [taxon 1280]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12757095/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12757095/full.md

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Source: https://tomesphere.com/paper/PMC12757095