# High-Grade Round Cell Neoplasm Presenting as an Anterior Mediastinal Mass With Features of Desmoplastic Round Cell Tumour

## TL;DR

A young female presented with an unusual case of high-grade round cell tumor resembling desmoplastic small round cell tumor, which appeared as a mediastinal mass.

## Contribution

This paper reports a rare case of DSRCT in a young female with an unusual clinical presentation.

## Key findings

- The patient exhibited anaphylactic reactions to blueberries before the tumor was detected.
- Histopathology confirmed a high-grade round cell tumor with features of desmoplastic small round cell tumor.
- The case emphasizes the need for early recognition and multidisciplinary management of such tumors.

## Abstract

Desmoplastic small round cell tumours (DSRCT) are highly aggressive neoplasms typically affecting adolescent and young adult males. We present a rare case of high-grade round cell tumour with features of DSRCT in a young female who initially presented with anaphylactic reactions to blueberries, which, on further evaluation, revealed an anterior mediastinal mass. Contrast-enhanced CT (CECT) of the thorax demonstrated a large, round cell tumour encasing multiple mediastinal structures, later confirmed by histopathology. The patient was offered combined chemotherapy and radiotherapy; however, she opted to leave against medical advice. This case highlights an unusual presentation of DSRCT and underscores the importance of early recognition and multidisciplinary management.