# Mapping the Scientific Landscape of Schizophrenia Genetics (2020–2025): A Bibliometric and Scientometric Study of Global Trends and Collaborations

## TL;DR

This study maps global trends and collaborations in schizophrenia genetics research from 2020 to 2025 using bibliometric and scientometric methods.

## Contribution

The study introduces a comprehensive analysis of thematic evolution and collaboration networks in schizophrenia genetics using VOSviewer.

## Key findings

- Publications increased significantly from 2020 to 2022, then stabilized.
- Six major thematic clusters were identified, including genetic mechanisms and neuroimaging.
- The United States, China, and the United Kingdom were central hubs of international collaboration.

## Abstract

This study provides a comprehensive bibliometric and scientometric analysis of research trends in schizophrenia genetics from 2020 to 2025. Driven by rapid technological advances such as genome‐wide association studies (GWAS) and next‐generation sequencing (NGS), the field has experienced significant growth. The objective was to map the thematic evolution, key contributors, and collaboration networks shaping psychiatric genomics research.

An integrated bibliometric and scientometric approach was employed. A dataset of 5001 English‐language publications authored by 27,692 researchers was retrieved from PubMed, Scopus, and web of science (Wos) databases. Following deduplication and eligibility screening, VOSviewer (version 1.6.20) was used to generate network visualizations analyzing co‐authorship, keyword co‐occurrence, citation, and co‐citation patterns.

The analysis revealed a notable surge in publications after 2022, increasing from 431 articles in 2020 to 1,645 articles in 2022, before stabilizing above 900 publications annually in 2023 and 2024. Six major thematic clusters were identified: (1) genetic and cellular mechanisms; (2) neurochemical and behavioral studies; (3) neuroimaging; (4) clinical and epidemiological features including polygenic risk scoring; (5) methodological approaches; and (6) comorbidities with pharmacogenetic implications. Prominent contributors included Ole A. Andreassen and Vince D. Calhoun, while the United States, China, and the United Kingdom emerged as central hubs of international collaboration.

This study elucidates the leading researchers, prevailing themes, and collaborative networks driving schizophrenia genetics research from 2020 to 2025. The findings demonstrate the efficacy of bibliometric and scientometric methods, particularly VOSviewer, in revealing the dynamic landscape of psychiatric genomics and guiding future multidisciplinary research efforts.This graphical abstract illustrates the integrated workflow of the study “mapping the scientific landscape of schizophrenia genetics (2020–2025)”. The process combines bibliometric and scientometric analyses of 5,001 publications using VOSviewer to identify thematic clusters, key contributors, and international collaboration networks that define global research trends in schizophrenia genetics.

This graphical abstract illustrates the integrated workflow of the study‐ Mmapping the Sscientific Llandscape of Sschizophrenia Ggenetics (2020‐2025). The process combines bibliometric and scientometric analyses of 5,001 publications using VOSviewer to identify thematic clusters, key contributors, and international collaboration networks that define global research trends in schizophrenia genetics.