# First person – Marinus Thein

## TL;DR

This paper discusses the regulation of microtubules in the parasite Trypanosoma brucei and how they maintain structural integrity.

## Contribution

The study explores the effects of microtubule (de)tyrosination and its interaction with polyglutamylation in Trypanosoma brucei.

## Key findings

- Microtubule (de)tyrosination affects the morphology and motility of Trypanosoma brucei.
- There is cross-talk between microtubule tyrosination and polyglutamylation in the parasite.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping researchers promote themselves alongside their papers. Marinus Thein is first author on ‘
Effects of microtubule (de)tyrosination on the morphology and motility of Trypanosoma brucei and cross-talk with polyglutamylation’, published in BiO. Marinus is a PhD student in the lab of Professor Dr Klaus Ersfeld at University of Bayreuth, Bayreuth, Germany, investigating how the highly stable microtubule cytoskeleton of the parasite Trypanosoma brucei is regulated and how it achieves is structural integrity.