# Liposomal Nanosystems Versus Hydrogels in the Prevention and Treatment of Metabolic Diseases

**Authors:** Mihaela-Carmen Eremia, Ramona-Daniela Pavaloiu, Fawzia Sha’at, Dana Maria Miu, Gabriela Savoiu, Anca Daniela Raiciu

PMC · DOI: 10.3390/gels11110917 · Gels · 2025-11-16

## TL;DR

This review compares liposomal nanosystems and hydrogels for their potential in preventing and treating metabolic diseases like diabetes and obesity.

## Contribution

The paper provides a comparative analysis of liposomal nanosystems and hydrogels for their use in metabolic disease management.

## Key findings

- Liposomal nanosystems and hydrogels offer controlled delivery of bioactive compounds for metabolic disease treatment.
- Each system has distinct advantages and limitations in applicability for metabolic disorders.
- Advances in nanotechnology have enabled new platforms for nutrient delivery in metabolic disease prevention.

## Abstract

Liposomal nano-systems and hydrogels are two types of nano-technological systems that have promising applications in the prevention and treatment of metabolic diseases (diabetes, obesity, dyslipidemias, and metabolic syndrome), which are a major public health concern worldwide. Advances in nanotechnology and biomaterials have enabled the development of new platforms for the controlled delivery of nutrients or bioactive compounds in order to solve these issues. This review compares the characteristics, advantages, and limitations of these two systems, with a focus on their applicability in the prevention and treatment of metabolic diseases.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015), obesity (MONDO:0011122), metabolic syndrome (MONDO:0000816)

## Full-text entities

- **Diseases:** diabetes (MESH:D003920), metabolic syndrome (MESH:D024821), Metabolic Diseases (MESH:D008659), obesity (MESH:D009765), dyslipidemias (MESH:D050171)

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12652794/full.md

## References

163 references — full list in the complete paper: https://tomesphere.com/paper/PMC12652794/full.md

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Source: https://tomesphere.com/paper/PMC12652794