# Wine Industry Waste as a Source of Bioactive Compounds for Drug Use

**Authors:** Mariana Mesta-Corral, Nathiely Ramirez-Guzman, David Aguillón-Gutiérrez, Cristian Torres-León, Jorge Aguirre-Joya

PMC · DOI: 10.3390/ijms262210820 · International Journal of Molecular Sciences · 2025-11-07

## TL;DR

This paper explores how waste from the wine industry can be used to extract valuable bioactive compounds for drug development.

## Contribution

The paper reviews the potential of wine industry waste as a source of bioactive compounds using fermentation techniques.

## Key findings

- Wine industry waste contains bioactive compounds with applications in pharmaceuticals.
- Fermentation techniques can extract and transform these compounds into high-value products.
- The paper outlines the wine production process and the types of waste generated.

## Abstract

Wine is one of the oldest alcoholic beverages, produced from the fermentation of the grape Vitis vinifera. Currently, the wine industry is exploited worldwide in multiple regions, generating significant amounts of agro-industrial waste at different stages of the production chain. These wastes represent a source of environmental contamination due to the toxic nature of some of their compounds. From a biotechnological perspective, the by-products of the wine industry are an attractive source of bioactive compounds with potential applications in various fields, including food, pharmaceuticals, and cosmetics. The extraction of these compounds can be carried out using fermentation techniques that utilize microorganisms to facilitate the release and biotransformation of the desired metabolites through their enzymatic tools. This work provides a review of the history of the wine industry and its current activities, describes the wine production process, and outlines the waste generated during this process. The fermentation process is described as a biotechnological alternative for the valorization of these residues. This purpose enables their reintegration into the production chain through the extraction of high-value bioactive compounds with potential use as drugs in pharmacology.

## Linked entities

- **Species:** Vitis vinifera (taxon 29760)

## Full-text entities

- **Species:** Vitis vinifera (wine grape, species) [taxon 29760]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12652082/full.md

## References

105 references — full list in the complete paper: https://tomesphere.com/paper/PMC12652082/full.md

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Source: https://tomesphere.com/paper/PMC12652082