Correction: Almeida et al. Cell Reprogramming, Transdifferentiation, and Dedifferentiation Approaches for Heart Repair. Int. J. Mol. Sci. 2025, 26, 3063
Micael Almeida, José M. Inácio, Carlos M. Vital, Madalena R. Rodrigues, Beatriz C. Araújo, José A. Belo

Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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TopicsPluripotent Stem Cells Research · Congenital heart defects research · Tissue Engineering and Regenerative Medicine
1. Reference Correction
After the publication of the review article [1], one of the referenced manuscripts was found to have been retracted. To enhance the quality of the manuscript, we decided to replace the previous reference number 157 [2] from the original manuscript with the new reference [3] at the same position in the reference list.
Original reference number 157: Zhang, D.; Ning, J.; Ramprasath, T.; Yu, C.; Zheng, X.; Song, P.; Xie, Z.; Zou, M.H. Kynurenine Promotes Neonatal Heart Regeneration by Stimulating Cardiomyocyte Proliferation and Cardiac Angiogenesis. Nat. Commun. 2022, 13, 6371. https://doi.org/10.1038/s41467-022-33734-7.
New reference number 157: Zhang, X.; Ma, S.; Zhang, R.; Li, S.; Zhu, D.; Han, D.; Li, X.; Li, C.; Yan, W.; Sun, D.; et al. Oncostatin M-induced cardiomyocyte dedifferentiation regulates the progression of diabetic cardiomyopathy through B-Raf/Mek/Erk signaling pathway. Acta Biochim. Biophys. Sin. 2016, 48, 257–265. https://doi.org/10.1093/abbs/gmv137.
The overall numbering and ordering of the references remain unchanged.
2. Text Correction
We have updated the following sentence in the manuscript: “Key pathways involved in the process of dedifferentiation include kynurenine and the aryl hydrocarbon receptor (AHR)–proto-oncogene tyrosine-protein kinase Src (SRC)–yes-associated protein (YAP)/ERK pathway [157]. Kynurenine has been shown to stimulate CM proliferation and angiogenesis via the AHR-SRC-YAP/ERK pathway [157]. Another crucial factor in this process is the inflammatory cytokine oncostatin M (OSM) that activates the Ras/mitogen-activated protein kinase (MEK)/ERK pathway [158–160].”
We have inserted the following corrected paragraph: “Key pathways involved in the process of dedifferentiation include the inflammatory cytokine oncostatin M (OSM) that activates the Ras/mitogen-activated protein kinase (MEK)/ERK pathway [157–160].”
The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Almeida M. Inácio J.M. Vital C.M. Rodrigues M.R. Araújo B.C. Belo J.A. Cell Reprogramming, Transdifferentiation, and Dedifferentiation Approaches for Heart Repair Int. J. Mol. Sci.202526306310.3390/ijms 2607306340243729 PMC 11988544 · doi ↗ · pubmed ↗
- 2Zhang D. Ning J. Ramprasath T. Yu C. Zheng X. Song P. Xie Z. Zou M.H. Kynurenine Promotes Neonatal Heart Regeneration by Stimulating Cardiomyocyte Proliferation and Cardiac Angiogenesis Nat. Commun.202213637110.1038/s 41467-022-33734-736289221 PMC 9606021 · doi ↗ · pubmed ↗
- 3Zhang X. Ma S. Zhang R. Li S. Zhu D. Han D. Li X. Li C. Yan W. Sun D. Oncostatin M-induced cardiomyocyte dedifferentiation regulates the progression of diabetic cardiomyopathy through B-Raf/Mek/Erk signaling pathway Acta Biochim. Biophys. Sin.20164825726510.1093/abbs/gmv 13726837420 PMC 4885130 · doi ↗ · pubmed ↗
