# Deep Learning for Sex Estimation from Whole-Foot X-Rays: Benchmarking CNNs for Rapid Forensic Identification

**Authors:** Rukiye Çiftçi, İpek Atik, Özgür Eken, Monira I. Aldhahi

PMC · DOI: 10.3390/diagnostics15222923 · Diagnostics · 2025-11-19

## TL;DR

This paper shows that deep learning models, especially InceptionV3, can accurately estimate sex from foot X-rays, offering a fast and cost-effective alternative to DNA analysis in forensic identification.

## Contribution

The study introduces and benchmarks deep learning models for sex estimation using whole-foot radiographs, achieving state-of-the-art accuracy.

## Key findings

- InceptionV3 achieved 97.1% accuracy in sex estimation from foot X-rays.
- Deep learning outperformed traditional anthropometric methods and previously reported techniques.
- The approach is suitable for rapid forensic identification when DNA analysis is not feasible.

## Abstract

Background: Accurate sex estimation is crucial in forensic identification when DNA analysis is impractical or remains are fragmented. Traditional anthropometric approaches often rely on single bone measurements and yield moderate levels of accuracy. Objective: This study aimed to evaluate deep convolutional neural networks (CNNs) for automated sex estimation using entire foot radiographs, an approach rarely explored. Methods: Digital foot radiographs from 471 adults (238 men, 233 women, aged 18–65 years) without deformities or prior surgery were retrospectively collected at a single tertiary center. Six CNN architectures (AlexNet, ResNet-18, ResNet-50, ShuffleNet, GoogleNet, and InceptionV3) were trained using transfer learning (70/15/15 train–validation–test split, data augmentation). The model performance was assessed using accuracy, sensitivity, specificity, precision, and F1-score. Results: InceptionV3 achieved the highest accuracy (97.1%), surpassing previously reported methods (typically 72–89%), with balanced sensitivity (97.5%) and specificity (96.8%). ResNet-50 followed closely (95.7%), whereas simpler networks, such as AlexNet, underperformed (90%). Conclusions: Deep learning applied to whole-foot radiographs delivers state-of-the-art accuracy for sex estimation, enabling rapid, reproducible, and cost-effective forensic identification when DNA analysis is delayed or unavailable, such as in mass disasters or clinical emergency settings.

## Full-text entities

- **Diseases:** deformities (MESH:D009140)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12651919/full.md

## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12651919/full.md

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Source: https://tomesphere.com/paper/PMC12651919