Correction: López-Manzanares et al. Real-World Use of COMT Inhibitors in the Management of Patients with Parkinson’s Disease in Spain Who Present Early Motor Fluctuations: Interim Results from the REONPARK Study. Brain Sci. 2025, 15, 532
Lydia López-Manzanares, Juan García Caldentey, Marina Mata Álvarez-Santullano, Dolores Vilas Rolán, Jaime Herreros-Rodríguez, Berta Solano Vila, María Cerdán Sánchez, Tania Delgado Ballestero, Rocío García-Ramos, Ana Rodríguez-Sanz, Jesús Olivares Romero, José Blanco Ameijeiras

Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsParkinson's Disease Mechanisms and Treatments · Transcranial Magnetic Stimulation Studies · Neurological disorders and treatments
Text Correction
There was an error in the original publication [1]. In the Introduction Section, the following referenced sentence contains a misinterpretation: “Moreover, recent findings have indicated the benefit of adding opicapone at 50 mg to an additional 100 mg of levodopa in reducing OFF times in a cohort with early fluctuations [19]”. The sentence incorrectly suggests that the benefit arises from combining opicapone 50 mg with an additional 100 mg of levodopa, thus attributing to the referenced work a statement that differs from their original text. The correct interpretation is that opicapone 50 mg was more effective than an additional 100 mg of levodopa in reducing OFF time.
A correction has been made to the 5th paragraph of the Introduction Section.
The revised paragraph reads as follows: “Moreover, recent findings have indicated that adding opicapone 50 mg is more beneficial than adding an additional 100 mg of levodopa in reducing OFF times in a cohort with early fluctuations [19].”
The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1López-Manzanares L. García Caldentey J. Álvarez-Santullano M.M. Vilas Rolán D. Herreros-Rodríguez J. Solano Vila B. Cerdán Sánchez M. Delgado Ballestero T. García-Ramos R. Rodríguez-Sanz A. Real-World Use of COMT Inhibitors in the Management of Patients with Parkinson’s Disease in Spain Who Present Early Motor Fluctuations: Interim Results from the REONPARK Study Brain Sci.20251553210.3390/brainsci 1505053240426702 PMC 12110095 · doi ↗ · pubmed ↗
