Gallbladder Schwannoma: A Case Report and Literature Review

TL;DR

A rare case of gallbladder schwannoma is reported, highlighting its diagnostic challenges and excellent prognosis after surgery.

Contribution

Adds a new clinical case and literature review on the rare gallbladder schwannoma.

Findings

Gallbladder schwannomas lack distinctive clinical or radiological features and require histopathological confirmation.

Complete surgical excision results in excellent prognosis with no recurrence reported.

No age or gender predilection was observed in the reviewed cases.

Abstract

Background and Clinical Significance: Schwannoma is a benign, encapsulated neurogenic neoplasm that originates from Schwann cells of the peripheral nerve sheath. While these tumors may develop in virtually any anatomical location, gallbladder schwannomas are exceptionally rare. Case Presentation: A 56-year-old female patient underwent hepatic tumor resection and cholecystectomy following imaging findings suggestive of possible small hepatocellular carcinoma in the right hepatic lobe and biliary cystadenoma. Postoperative pathological examination confirmed that the liver lesion was a lymphoproliferative disorder and that the gallbladder lesion was a classic schwannoma. The patient recovered well with no evidence of disease recurrence during the two-month follow-up. Conclusions: Current literature indicates that the pathogenesis of gallbladder schwannomas remains unclear, with no apparent age or gender predilection. These lesions lack distinctive clinical or radiological features, necessitating histopathological confirmation. However, they demonstrate excellent prognosis, with no reported recurrence after complete surgical excision.

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