# Stress, Anxiety, and Self-Efficacy in Hypertension: Evidence from a Romanian Case—Control Study

**Authors:** Lucia Bubulac, Mirela Zivari, Irina Anca Eremia, Constantin Erena, Consuela-Mădălina Gheorghe, Iuliana-Raluca Gheorghe, Viorica Tudor, Claudia Florina Bogdan-Andreescu, Emin Cadar, Cristina-Crenguța Albu

PMC · DOI: 10.3390/diseases13110373 · 2025-11-13

## TL;DR

The study finds that stress, anxiety, and low self-efficacy are linked to hypertension in Romanian adults, suggesting psychological factors should be addressed in treatment.

## Contribution

This is the first systematic evaluation of psychological factors in hypertension management in Romania, highlighting region-specific insights.

## Key findings

- Hypertensive individuals reported higher stress and anxiety and lower self-efficacy compared to controls.
- Type A behavior was not associated with hypertension in this population.
- Psychosocial interventions could improve hypertension treatment adherence and outcomes.

## Abstract

Background: Hypertension and psychological distress often coexist, though evidence from Eastern Europe is still limited. Stress, anxiety, and self-efficacy influence blood pressure control and treatment adherence. Their effect on hypertension prevention and treatment has not been systematically evaluated in Romania. Aim: This study evaluated the associations between stress, anxiety, and self-efficacy in Romanian adults with and without hypertension to identify modifiable psychological factors relevant for integrated cardiovascular management. Methods: A retrospective case–control study was conducted among 215 adults, including individuals with hypertension and normotensive controls. Participants completed validated questionnaires assessing stress vulnerability, perceived stress, state and trait anxiety, self-efficacy, and Type A behavior, together with demographic and occupational data. Results: Hypertensive participants reported higher stress vulnerability, perceived stress, and anxiety, as well as lower self-efficacy, compared with controls. Type A behavior showed no association with hypertension. These differences remained consistent after accounting for demographic characteristics. Conclusions: Hypertension in Romanian adults is associated with a distinct psycho-emotional profile characterized by elevated stress and anxiety and reduced self-efficacy. Type A personality showed no association. The results emphasize the importance of recognizing and addressing modifiable psychological determinants in hypertension care. Integrating psychosocial assessment with personalized interventions, including mindfulness-based approaches, digital health support, and nurse-led telemonitoring, could improve treatment adherence, reduce emotional burden, and contribute to overall cardiovascular health. This region-specific evidence supports expanding hypertension management to include psychological care alongside standard medical approaches.

## Full-text entities

- **Diseases:** Anxiety (MESH:D001007), Hypertension (MESH:D006973), Type A personality (MESH:D010554)

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12650833/full.md

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Source: https://tomesphere.com/paper/PMC12650833