# Double-Layer Simplified Complex Interval Neural Network Stacking for Blood Glucose Prediction of Continuous Glucose Monitoring System

## TL;DR

This paper introduces a new neural network model for predicting blood glucose levels using continuous monitoring data, offering better accuracy and stability.

## Contribution

The novel contribution is a double-layer SCINet stacking model that improves glucose prediction accuracy and generalization.

## Key findings

- The proposed model outperforms existing methods in glucose prediction accuracy.
- It demonstrates high stability across varying prediction horizons and patient datasets.

## Abstract

Diabetes is a metabolic disorder characterized by persistent hyperglycemia, with its incidence steadily rising worldwide. Blood glucose monitoring is a core measure in diabetes management, and continuous glucose monitoring provides more comprehensive and accurate glucose data compared to traditional fingerstick testing. To collect continuous glucose data from patients, precise glucose prediction algorithms can help them better control their blood glucose fluctuations. Therefore, by addressing the issues of low prediction accuracy, complex input features, and poor generalization performance in existing glucose prediction methods, this paper proposes a glucose prediction model based on a double-layer SCINet stack using time-series analysis methods. SCINet effectively captures multi-scale dynamic features in time-series data through recursive down-sampling and convolution operations, making it suitable for glucose prediction tasks. Experimental data were sourced from real-world continuous glucose monitoring records of patients at Yixing People’s Hospital. Model input features were optimized through variable selection and data preprocessing, with predictive performance validated on a test dataset. The results demonstrate that the proposed model outperforms existing time-series prediction models across varying prediction horizons and patient datasets, exhibiting high predictive accuracy and stability.