# Posterior laryngeal web in an adult with GERD-associated globus pharyngeus: A rare case managed conservatively

**Authors:** Samiksha Lamichhane, Asitama Sarkar, Silvia Maharjan, Roshan Shrestha, Shritik Devkota, Prajjwal Pokhrel, Harsimran Bhatia

PMC · DOI: 10.1093/omcr/omaf231 · 2025-11-26

## TL;DR

A rare case of a posterior laryngeal web in an adult with GERD was successfully treated with anti-reflux therapy, suggesting a possible link between GERD and web formation.

## Contribution

This case report presents a rare instance of a posterior laryngeal web managed conservatively without intubation or trauma history.

## Key findings

- A 24-year-old male with GERD was found to have a posterior laryngeal web.
- Symptoms improved significantly with anti-reflux therapy.
- The case suggests a possible association between GERD and posterior laryngeal web formation.

## Abstract

Laryngeal webs are rare structural anomalies, typically anterior in location when congenital. Posterior laryngeal webs are exceedingly uncommon and are most often acquired, with common associations including prior intubation and gastroesophageal reflux disease (GERD). GERD-induced laryngeal inflammation is a proposed mechanism for web formation due to chronic mucosal irritation and fibrosis. We present the case of a 24-year-old male with recurrent globus pharyngeus and chest discomfort, found to have a posterior laryngeal web in the absence of prior intubation or trauma. The patient was diagnosed with GERD and demonstrated marked symptomatic improvement following anti-reflux therapy. This case highlights the potential link between GERD and posterior laryngeal web formation, emphasizing the role of conservative management in select cases. Further research is warranted to explore the pathophysiological relationship between GERD and laryngeal structural changes, as well as to refine treatment strategies.

## Linked entities

- **Diseases:** gastroesophageal reflux disease (MONDO:0007186), GERD (MONDO:0007186)

## Full-text entities

- **Diseases:** laryngeal inflammation (MESH:D007249), GERD (MESH:D005764), fibrosis (MESH:D005355), mucosal irritation (MESH:D001523), trauma (MESH:D014947), globus pharyngeus (MESH:D000079564), Laryngeal webs (MESH:C563636)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12648547/full.md

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Source: https://tomesphere.com/paper/PMC12648547