# Anesthetic Management and Considerations of Diaphragmatic Pacemaker Placement for Cervical Spine Injury: A Case Report

**Authors:** Sarah Sun, Dylan Irvine, Gordon Hubbell, Raul Bermudez-Velez, Imani Thornton

PMC · DOI: 10.7759/cureus.95441 · 2025-10-26

## TL;DR

This case report discusses the anesthetic challenges and successful diaphragmatic pacemaker placement in a patient with a high cervical spinal injury.

## Contribution

The paper presents a novel case highlighting anesthetic strategies for diaphragmatic pacemaker implantation in cervical spine injury patients.

## Key findings

- Diaphragmatic pacemakers can reduce ventilator dependence in high cervical SCI patients.
- Anesthetic management must preserve diaphragmatic function and address autonomic instability.
- Interdisciplinary planning and vigilant monitoring are crucial to avoid device-related complications.

## Abstract

High cervical spinal cord injuries (SCIs) can lead to diaphragmatic paralysis, necessitating long-term mechanical ventilation. Diaphragmatic pacemakers (DPs) offer an alternative by stimulating the phrenic nerve to restore diaphragmatic function, thereby improving quality of life and reducing ventilator dependence. However, anesthetic management for DP placement presents unique challenges due to the need to preserve diaphragmatic activity and manage autonomic instability. This case reports a 35-year-old male with complete C4 SCI resulting in quadriplegia and respiratory failure requiring mechanical ventilation. After multiple interventions, including spinal fusion and tracheostomy, he underwent DP placement to reduce ventilator dependency. The patient was successfully transitioned to DP postoperatively and discharged from the hospital on room air via a tracheostomy collar. DP is a valuable intervention for high cervical SCI patients but requires anesthetic strategies that preserve diaphragmatic function and manage common complications such as pneumothorax, autonomic dysreflexia, and ventilator challenges with abdominal insufflation. Avoiding muscle relaxants, continuous diaphragmatic monitoring, and proactive hemodynamic management are essential. The literature highlights rare but serious device-related complications, emphasizing the importance of vigilant intraoperative monitoring and interdisciplinary planning. As DP becomes more accessible, particularly in community hospitals, anesthesiologists must be prepared to navigate its perioperative challenges. This case underscores the importance of tailored anesthetic approaches to support safe and effective DP implantation.

## Linked entities

- **Diseases:** quadriplegia (MONDO:0001590), respiratory failure (MONDO:0021113)

## Full-text entities

- **Diseases:** pneumothorax (MESH:D011030), respiratory failure (MESH:D012131), SCIs (MESH:D013119), Cervical Spine Injury (MESH:D002575), dysreflexia (MESH:D020211), quadriplegia (MESH:D011782), diaphragmatic paralysis (MESH:D012133)
- **Chemicals:** DP (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12648449/full.md

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Source: https://tomesphere.com/paper/PMC12648449