# Ewing’s Sarcoma of the Calcaneus

**Authors:** Hafsa Jamal Eddine, Othmane Zouiten, Leila Afani, Mohamed El Fadli, Rhizlane Belbaraka

PMC · DOI: 10.7759/cureus.95412 · 2025-10-25

## TL;DR

This paper presents a rare case of Ewing’s sarcoma in the heel bone of a 30-year-old woman, highlighting its aggressive progression and the need for early diagnosis.

## Contribution

The novelty lies in reporting a rare calcaneal location of Ewing’s sarcoma in an adult, emphasizing diagnostic and clinical challenges.

## Key findings

- Ewing’s sarcoma was diagnosed in the calcaneus with bone metastases at presentation.
- The patient’s condition progressed rapidly despite treatment, leading to death from pulmonary embolism.
- The case underscores the importance of early recognition and comprehensive evaluation for aggressive tumors like ES.

## Abstract

Ewing’s sarcoma (ES) is a rare malignant bone tumor that usually affects long bones and the pelvis and is most frequently diagnosed during childhood and adolescence.

We report the case of a 30-year-old woman who presented with calcaneus pain and swelling. At the time of diagnosis, imaging tests showed a calcaneal lesion with bone metastases. ES was confirmed by histopathological examination. The patient was treated with palliative chemotherapy and surgery due to the progression of the swelling and local secondary infection. Postoperative computed tomography of the thorax, abdomen, and pelvis revealed lung and bone progression. Second-line chemotherapy was planned, but unfortunately, the patient died of pulmonary embolism.

This case illustrates the aggressive nature of calcaneal ES and emphasizes the importance of early recognition and comprehensive evaluation.

## Linked entities

- **Diseases:** Ewing’s sarcoma (MONDO:0012817), pulmonary embolism (MONDO:0005279)

## Full-text entities

- **Diseases:** bone tumor (MESH:D001859), calcaneus pain (MESH:D010146), calcaneal lesion (MESH:D036982), pulmonary embolism (MESH:D011655), ES (MESH:D012512), infection (MESH:D007239), bone metastases (MESH:D009362), swelling (MESH:D004487)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12648448/full.md

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Source: https://tomesphere.com/paper/PMC12648448