# Case Report: Three cases of drug-coated balloon-only strategy for coronary artery lesions with aneurysms in the chronic phase

**Authors:** Yu Sugawara

PMC · DOI: 10.3389/fcvm.2025.1710371 · 2025-11-12

## TL;DR

This case report describes three patients with coronary artery aneurysms successfully treated using drug-coated balloons, showing favorable outcomes.

## Contribution

The paper presents a novel treatment approach using drug-coated balloons for coronary lesions with aneurysms, which is uncommonly reported.

## Key findings

- Drug-coated balloons were used successfully in three cases of coronary artery lesions with aneurysms.
- Acute outcomes and chronic follow-up results were favorable in all three cases.
- Paclitaxel drug-coated balloons showed potential for treating complex coronary artery conditions.

## Abstract

Coronary aneurysms are rare; therefore, treatment strategies for coronary lesions with aneurysms remain elusive. We describe three cases of coronary artery lesions with aneurysms in patients treated with drug-coated balloons (DCBs).

Case 1 had ST-segment elevation myocardial infarction with a right coronary artery aneurysm treated with a paclitaxel DCB. Case 2 had stenoses of the left anterior descending artery and diagonal branch, along with a coronary aneurysm treated using paclitaxel DCBs. Case 3 had a calcified left anterior descending artery with an aneurysm treated using a paclitaxel DCB. The acute outcomes of these cases were favorable, and prognoses based on follow-up computed tomography angiography findings in the chronic phase were also favorable.

DCBs may be one option for treating coronary artery stenosis or occlusion.

## Linked entities

- **Chemicals:** paclitaxel (PubChem CID 36314)
- **Diseases:** myocardial infarction (MONDO:0005068)

## Full-text entities

- **Diseases:** myocardial infarction (MESH:D009203), coronary lesions (MESH:D003327), coronary artery lesions (MESH:D003324), aneurysm (MESH:D000783), coronary artery stenosis or occlusion (MESH:D023921), Coronary aneurysms (MESH:D003323), stenoses (MESH:D003251)
- **Chemicals:** paclitaxel (MESH:D017239), DCB (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12648217/full.md

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Source: https://tomesphere.com/paper/PMC12648217