# Unveiling the intermediate tumour: a case report of uterine smooth muscle tumour of uncertain malignant potential and review of magnetic resonance imaging features

**Authors:** Phoebe Hay Pui Yeung, Siu Chun Wong, Ting Wong, Yuen Fun Mak, Ka Yu Cheng, Yat Yee Shizuka Chan, Tsz Man Mimi Fung

PMC · DOI: 10.1093/bjrcr/uaaf053 · 2025-11-09

## TL;DR

This paper presents a case of a rare uterine tumor called STUMP and discusses its MRI features to help distinguish it from benign and malignant tumors.

## Contribution

The paper provides a case report and MRI insights to improve the diagnosis of STUMP.

## Key findings

- STUMP lies between benign and malignant uterine tumors and can progress to cancer.
- MRI features can help differentiate STUMP from benign leiomyomas.
- Multidisciplinary care is essential for managing STUMP due to its unpredictable behavior.

## Abstract

Uterine smooth muscle tumour of uncertain malignant potential (STUMP) is a rare and diagnostically challenging entity, lying on the spectrum between benign leiomyomas and malignant leiomyosarcomas. Its unpredictable biological behaviour and potential for metastasis and progression to leiomyosarcoma necessitate surgical removal and long-term surveillance for late recurrence and malignant transformation. We present a case of uterine STUMP in a 49-year-old woman with a large uterine mass exhibiting suspicious magnetic resonance imaging (MRI) features preoperatively. She underwent a hysterectomy with histological confirmation of STUMP. Through radiologic-pathologic correlation, we highlight key MRI features that can suggest the diagnosis of STUMP and aid in differentiating it from benign leiomyomas. While differentiating STUMP from leiomyosarcoma on imaging remains challenging due to its rarity and overlapping imaging characteristics, imaging plays a crucial role in detecting complications and guiding follow-up. Multidisciplinary management in tertiary centres with gynaecologic oncology expertise is essential for comprehensive patient care.

## Linked entities

- **Diseases:** leiomyosarcoma (MONDO:0005058)

## Full-text entities

- **Diseases:** metastasis (MESH:D009362), benign leiomyomas (MESH:D007889), STUMP (MESH:D019042), tumour (MESH:D009369), leiomyosarcoma (MESH:D007890), uterine mass (MESH:C536030)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12648055/full.md

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Source: https://tomesphere.com/paper/PMC12648055