# Wrong place at the right time, a case of primary bronchial myoepithelial carcinoma

**Authors:** Hermione Jemmett, Sanjeet Singh Avtaar Singh, Ella Bauwens, Katherine Quiohilag, Malcolm Will

PMC · DOI: 10.1093/jscr/rjaf927 · 2025-11-25

## TL;DR

This paper presents a rare case of primary bronchial myoepithelial carcinoma and highlights the importance of early detection and surgical treatment for this uncommon lung cancer.

## Contribution

The paper contributes a detailed clinical case report of a rare lung malignancy with successful surgical management.

## Key findings

- A 78-year-old male was diagnosed with a high-grade myoepithelial carcinoma in the bronchus.
- Surgical resection with a bronchial sleeve upper lobectomy achieved complete tumor removal.
- The patient had no recurrence after follow-up imaging.

## Abstract

Primary bronchial myoepithelial carcinoma is a rare neoplasm, accounting for less than 1% of all primary lung malignancies. These tumours typically arise from submucosal tracheobronchial glands and are resistant to chemotherapy and radiotherapy, making surgical resection the preferred treatment. We present the case of a 78-year-old male who was incidentally found to have a right upper lobe endobronchial lesion following investigation for a chest infection. Imaging revealed a 3.8 cm obstructive mass in the right main bronchus. Bronchoscopic biopsy confirmed a high-grade myoepithelial carcinoma. He underwent a serratus-sparing thoracotomy with a bronchial sleeve upper lobectomy and mediastinal lymphadenectomy. The anastomosis was reinforced with a pedicled thymo-pericardial diaphragmatic fat flap. Postoperative recovery was complicated by pneumonia, delirium, and electrolyte imbalance, all of which resolved with appropriate management. Histopathology confirmed complete resection. Follow-up imaging showed no recurrence. This case underscores the importance of early recognition and meticulous surgical management in treating this rare pulmonary malignancy.

## Linked entities

- **Diseases:** pneumonia (MONDO:0005249), delirium (MONDO:0045057)

## Full-text entities

- **Diseases:** chest infection (MESH:D002637), Primary bronchial myoepithelial carcinoma (MESH:D002283), pneumonia (MESH:D011014), myoepithelial carcinoma (MESH:D009208), neoplasm (MESH:D009369), delirium (MESH:D003693), endobronchial lesion (MESH:D009059), lung malignancies (MESH:D008175)

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12646253/full.md

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Source: https://tomesphere.com/paper/PMC12646253