# Anxiety, depression, and HRQoL in pediatric microtia patients following ear reconstruction: a cross-sectional study

**Authors:** Xinyi Liu, Ying Huang, Lin Yang, Enming Zhang, Jiafei Yang, Liujing Meng, Liping Ma, Zhengzhen Fu, Yanchun Zhou, Weiwei Bian

PMC · DOI: 10.3389/fpsyt.2025.1625342 · 2025-11-11

## TL;DR

This study found that children with microtia experience anxiety, depression, and lower quality of life after ear reconstruction surgery, highlighting the need for psychological and pain management support.

## Contribution

The study identifies specific psychological and socio-demographic factors affecting quality of life in pediatric microtia patients post-surgery.

## Key findings

- 21.7% of patients showed anxiety symptoms and 17.8% showed depression symptoms post-surgery.
- Anxiety and depression were moderately correlated with lower HRQoL scores.
- Residence, surgery type, pain, and depression were significant predictors of HRQoL.

## Abstract

The aim of this study was to evaluate the levels of anxiety, depression, and health-related quality of life (HRQoL) in patients with congenital microtia after ear recontruction surgery and identify influencing factors of HRQoL.

A cross-sectional study was conducted in 152 patients with congenital microtia (aged 8–18 years) who underwent ear reconstruction at a tertiary hospital in Shanghai from April 2023 to September 2024. The assessment tools, including the Hospital Anxiety and Depression Scale, and the Pediatric Quality of Life Inventory Version 4.0 Generic Core Scales, were used to assess symptoms of anxiety, symptoms of depression and HRQoL within 24 hours postoperatively. Multiple linear regression was performed to explore the factors affecting HRQoL.

Postoperatively, 21.7% of patients with congenital microtia reported symptoms of anxiety, and 17.8% reported symptoms of depression. Patients with congenital microtia have significantly lower HRQoL scores than the healthy norm group. Anxiety and depression showed moderate negative correlations with HRQoL score (r = -0.433 and -0.486, respectively, p < 0.001). Multivariate analysis showed that residence (95% CI: -6.661, -0.902, p = 0.010), surgery type (95% CI: 2.113, 9.496, p = 0.002), pain score (95% CI: -1.836, -0.031, p = 0.043) and depression score (95% CI: -1.644, -0.318, p = 0.004) were significantly associated with HRQoL in patients with congenital microtia after surgery.

Patients with congenital microtia experience significant psychological distress and reduced quality of life after ear reconstruction surgery, with anxiety, depression, pain, and socio-demographic factors playing critical roles. These findings underscore the necessity of an integrated care model that incorporates psychological evaluation, pain management, and personalized support to improve mental health and quality of life in these patients.

## Linked entities

- **Diseases:** microtia (MONDO:0010920)

## Full-text entities

- **Diseases:** congenital microtia (MESH:D065817), Depression (MESH:D003866), pain (MESH:D010146), Anxiety (MESH:D001007)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12645626