# Artificial Intelligence in Bone Fracture Detection: A Review of Evidence, Limitations, and Clinical Integration

**Authors:** Ahmed Elkohail, Ali Soffar, Ashis Paul, Larisa Radu, Mohamed Wasim Shaffe Ahamed, Ahmed Swealem, Aqil Ahamed Mohideen Ahamed Sha, Haritha Haridas Mandoth Veetil, Mohammed S Millat, Rhia Shah

PMC · DOI: 10.7759/cureus.97674 · Cureus · 2025-11-24

## TL;DR

This paper reviews how AI improves bone fracture detection in medical imaging, highlighting its benefits and challenges in clinical use.

## Contribution

The paper provides a comprehensive review of AI's role in fracture detection, emphasizing clinical integration challenges and quality considerations.

## Key findings

- AI systems show high sensitivity and specificity (0.85-0.95) in detecting bone fractures across imaging modalities.
- AI supports workflow triage and improves reader confidence in orthopedic decision-making.
- Challenges include limited generalizability, inconsistent standards, and implementation costs.

## Abstract

Medical imaging is rapidly being improved by artificial intelligence (AI), with deep-learning systems performing well in radiography, CT, and MRI for fracture detection, classification, and localization. This narrative review examined recent evidence spanning different types of bone fractures, alongside soft-tissue injuries relevant to orthopedic decision-making. Across multiple meta-analyses and external validations, reported sensitivities and specificities commonly range from 0.85 to 0.95, while AI also supports workflow triage and reader confidence. Persistent gaps include limited generalizability, inconsistent reference standards, spectrum bias, regulatory and ethical challenges, and implementation costs. We outline pragmatic quality considerations and emphasize prospective, multi-center trials and transparent reporting for safe clinical integration. AI should augment clinicians, improving speed, accuracy, and overall patient outcomes.

## Full-text entities

- **Diseases:** injuries (MESH:D014947), Bone Fracture (MESH:D050723)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12643460/full.md

## References

59 references — full list in the complete paper: https://tomesphere.com/paper/PMC12643460/full.md

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Source: https://tomesphere.com/paper/PMC12643460