# Temporal trend of hospitalization for chronic venous disease in Brazil from 2014 to 2023

## TL;DR

Hospitalization rates for chronic venous disease in Brazil remained stable overall from 2014 to 2023, but some regions and age groups saw significant declines.

## Contribution

This study provides a detailed analysis of regional and demographic trends in CVD hospitalizations in Brazil over a nine-year period.

## Key findings

- Overall hospitalization rates for CVD showed no significant change (β = -3.233; p = 0.060).
- Significant reductions were observed in the Northeast, Southeast, and South regions.
- Women aged 50-69 showed stable hospitalization rates, highlighting a need for targeted interventions.

## Abstract

Chronic Venous Disease (CVD) of the lower extremities (LEs) is a condition with significant prevalence and hospital admission rates.

To analyze temporal trends in hospitalization due to CVD from 2014 to 2023 in Brazil.

An ecological time series study of CVD-related hospitalization using data from the Brazilian Unified Health System. Data were analyzed using simple linear regression with annual variation (β) and percentage changes, with significance set at p < 0.05.

A total of 1,091,733 CVD-related hospital admissions were recorded for the period assessed. The overall rate showed a stable trend (β = -3.233; p = 0.060), with an average of 73.98 hospital admissions per 100,000 inhabitants. Statistically significant reductions were observed in the Northeast (β = -1.275; p = 0.042), Southeast (β = -4.262; p = 0.044), and South (β = -7.282; p = 0.012) regions of Brazil. The North and Midwest regions had stable rates. Both sexes showed stable trends, although hospital admission rates were higher among women. Significant reductions were found among men aged 20 and older and among women aged 20 - 49 and 70 and older. Stable rates were observed in women aged 50-69.

Overall hospital admission rates for CVD in Brazil remained stable between 2014 and 2023. However, regional and age-specific differences highlight the need for targeted public health strategies, particularly for women aged 50-69 and residents of the North and Midwest regions.

A doença venosa crônica dos membros inferiores (DVC) é uma enfermidade de importante prevalência e taxa de hospitalização.

Analisar a tendência temporal de hospitalizações por DVC no Brasil entre 2014 e 2023.

Estudo ecológico de séries temporais de hospitalização por DVC utilizando dados do Sistema de Informação Hospitalar do Sistema Único de Saúde. Utilizou-se regressão linear simples, com variação média anual das taxas (β) e variação percentual, considerando p < 0,05.

Analisaram-se 1.091.733 internações por DVC no Brasil no período estudado. A taxa geral (β = -3,233; p = 0,060) apresentou tendência de estabilidade, com média de 73,98 internações por 100 mil habitantes. Houve redução estatisticamente significativa no Nordeste (β = -1,275; p = 0,042), Sudeste (β = -4,262; p = 0,044) e Sul (β = -7,282; p = 0,012). Observou-se estabilidade tanto em homens (β = -1,439; p = 0,052) quanto em mulheres (β = -4,892; p = 0,063), com taxas mais elevadas entre estas. Homens de 20 a 80 anos ou mais (p < 0,05) e mulheres de 20 a 49 e 70 anos ou mais (p < 0,05) apresentaram redução significativa.

A taxa geral de internações por DVC no Brasil mostrou-se estável. Houve redução nas regiões Nordeste, Sudeste e Sul, e estabilidade nas demais. Ambos os sexos apresentaram tendência estável. Verificou-se redução entre homens de 20 a 80 anos ou mais e mulheres de 20 a 49 e 70 anos ou mais, com estabilidade apenas em mulheres de 50 a 69 anos.