# Efficacy of using the mechanochemical endovenous ablation to treat chronic venous ulcers: case report and literature review

**Authors:** Arthur Souza Magnani, Thiago Faiad Name Villari, Alexandre de Azevedo Melo, Marcela Juliano da Silva, Dafne Braga Diamante Leiderman, Arthur Souza Magnani, Thiago Faiad Name Villari, Alexandre de Azevedo Melo, Marcela Juliano da Silva, Dafne Braga Diamante Leiderman

PMC · DOI: 10.1590/1677-5449.202301732 · Jornal Vascular Brasileiro · 2025-11-10

## TL;DR

A 47-year-old man with a chronic leg ulcer and vein issues was successfully treated with a minimally invasive mechanochemical ablation procedure, leading to complete healing and symptom relief.

## Contribution

Demonstrates the effectiveness of mechanochemical ablation in treating venous ulcers with deep vein insufficiency, a less common scenario.

## Key findings

- The patient's venous ulcer healed completely 9 weeks after the ablation procedure.
- Symptoms like leg heaviness and dermatitis improved significantly post-treatment.
- Duplex ultrasound confirmed successful closure of the great saphenous vein with no complications.

## Abstract

This case report presents the successful treatment of a 47-year-old male patient with a venous ulcer of the leg associated to deep and superficial venous insufficiency. The patient presented with a non-healing venous ulcer on his leg, ocher dermatitis and heaviness of the leg, which interfered with work activities. Duplex ultrasound revealed deep venous insufficiency (popliteal vein), incompetence of the great saphenous and indirect perforating veins. The treatment involved ablation of the great saphenous vein using Flebogrif®, a specific mechanochemical ablation device. Following the treatment, the patient experienced significant improvement in his symptoms and venous ulcer was completely healed 9 weeks after the procedure and one year after that. Duplex ultrasound performed after the treatment confirmed the successful closure of the great saphenous vein. This case report highlights the effectiveness of mechanochenical ablation in the management of venous ulcers, even when deep venous insufficiency is involved.

Este relato de caso apresenta o tratamento bem-sucedido de um paciente do sexo masculino, de 47 anos, com úlcera venosa de membro inferior associada à insuficiência venosa profunda e superficial. O paciente apresentava úlcera venosa crônica, dermatite ocre e dor, o que prejudicava suas atividades laborais. O ultrassom Doppler revelou insuficiência venosa profunda, incompetência da veia safena magna e perfurantes indiretas no leito da úlcera. Foi realizada ablação mecanoquímica da veia safena magna com Flebogrif®. A úlcera venosa cicatrizou em 9 semanas após o procedimento e mantém-se cicatrizada no acompanhamento de 1 ano. Houve melhora dos sintomas, sem complicações relacionadas ao procedimento. Este relato de caso destaca a eficácia da ablação mecanoquímica no tratamento de úlceras venosas, mesmo na presença de insuficiência venosa profunda.

## Full-text entities

- **Diseases:** ocher dermatitis (MESH:D003872), deep and superficial venous insufficiency (MESH:D014689), popliteal vein (MESH:D011151), incompetence of the (MESH:D001022), veins (MESH:D000071078), venous ulcer (MESH:D014647)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12642920/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12642920/full.md

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Source: https://tomesphere.com/paper/PMC12642920