# Expanding disease resistance: engineered NLRS for broad-spectrum protection

**Authors:** Tingting Zhou, Jiajun Wang, Yunjing Wang

PMC · DOI: 10.1186/s43897-025-00217-4 · Molecular Horticulture · 2025-11-24

## Full-text entities

- **Genes:** ARC (activity regulated cytoskeleton associated protein) [NCBI Gene 23237] {aka Arg3.1, hArc}, PGR (progesterone receptor) [NCBI Gene 5241] {aka NR3C3, PR}, PDE7A (phosphodiesterase 7A) [NCBI Gene 5150] {aka HCP1, PDE7}
- **Diseases:** NLRs (MESH:D011488), infection (MESH:D007239), viral infection (MESH:D014777)
- **Chemicals:** NIa-Pro (-), ROS (MESH:D017382)
- **Species:** Turnip mosaic virus (no rank) [taxon 12230], Oryza sativa (Asian cultivated rice, species) [taxon 4530], Arabidopsis thaliana (mouse-ear cress, species) [taxon 3702], Pepper mottle virus (no rank) [taxon 12209], Potyvirus (genus) [taxon 12195], Nicotiana benthamiana (species) [taxon 4100], Symbiodinium sp. MV (species) [taxon 231000], Chilli veinal mottle virus (no rank) [taxon 52280], Plum pox virus (no rank) [taxon 12211], Tobacco etch virus (no rank) [taxon 12227], Soybean mosaic virus (no rank) [taxon 12222], Potato virus Y (no rank) [taxon 12216], Agrobacterium (genus) [taxon 357]
- **Cell lines:** aTm-22 — Mus musculus (Mouse), Spontaneously immortalized cell line (CVCL_ZJ87), -22 — Mus musculus (Mouse), Hybridoma (CVCL_B4FN)

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Source: https://tomesphere.com/paper/PMC12642151