# A Rare Cause of Upper Gastrointestinal Bleeding: Superior Mesenteric Artery Aneurysm

**Authors:** Natalia Sinou, Despoina Milonaki, Aristeidis Papadopoulos, Sophia Ispanopoulou, Georgios Meimaris

PMC · DOI: 10.7759/cureus.95311 · Cureus · 2025-10-24

## TL;DR

This paper reports a rare case of upper gastrointestinal bleeding caused by a ruptured superior mesenteric artery aneurysm and highlights the importance of prompt diagnosis and endovascular treatment.

## Contribution

The paper presents a clinical case emphasizing the underdiagnosed and life-threatening nature of SMA aneurysms as a cause of GI bleeding.

## Key findings

- SMA aneurysms are a rare but critical cause of upper GI bleeding with high mortality if untreated.
- Endovascular embolization is a safe and effective treatment option for SMA aneurysm-related bleeding.
- Prompt diagnosis and intervention are crucial for successful patient outcomes.

## Abstract

Superior mesenteric artery (SMA) aneurysms are a rare cause of gastrointestinal (GI) bleeding that is usually underdiagnosed. These conditions can lead to severe complications, making prompt treatment essential.

We report a case of a 87-year-old female patient admitted for intense pain in the abdominal area. After a 24-hour hospital stay, she had an episode of hematochezia, hematemesis, and intense epigastric pain. Upper GI endoscopy revealed a foreign body in the duodenum, which was removed. The bleeding and the hemodynamic instability were persistent even after the removal of the foreign body. A CT angiography revealed an aneurysm in the SMA with active contrast extravasation. The patient underwent endovascular treatment with coil embolization, achieving complete hemodynamic stabilization without complications.

GI bleeding from an aneurysm in the SMA is an unusual but critical entity with high mortality (40-60%); thus, rupture of the SMA aneurysm should always be considered in the differential diagnosis in cases with persistent GI bleeding. Regarding the hemodynamic stability of the patient or the patient’s overall clinical condition, the available treatment options include endoscopic interventions or open surgery. Endovascular treatment offers a safe and effective alternative to open surgery, with favorable outcomes.

Prompt diagnosis and, most of the time, endovascular embolization are crucial for successful management of SMA aneurysm-related upper GI bleeding.

## Full-text entities

- **Diseases:** Aneurysm (MESH:D000783), epigastric pain (MESH:D010146), Bleeding (MESH:D006470), Upper (MESH:D012141), GI bleeding (MESH:D006471), rupture (MESH:D012421), hematemesis (MESH:D006396), SMA aneurysm (MESH:D013478)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12641384/full.md

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Source: https://tomesphere.com/paper/PMC12641384