# COVID-19-Induced Left Atrial Appendage Thrombus

## TL;DR

This paper reports a case where a patient with heart issues and a history of bleeding developed a dangerous blood clot in the heart due to COVID-19.

## Contribution

The novelty lies in highlighting the rare but serious complication of left atrial appendage thrombus in a patient with multiple risk factors during a COVID-19 infection.

## Key findings

- A patient with atrial fibrillation and bleeding history developed a large left atrial appendage thrombus during a COVID-19 infection.
- The case illustrates the complex relationship between hypercoagulability from COVID-19, cardiac arrhythmia, and bleeding risk.
- Early recognition and management of thromboembolic risk are emphasized in high-risk patients with overlapping conditions.

## Abstract

Left atrial appendage (LAA) thrombus formation is a clinically significant complication that can occur in patients with atrial fibrillation (AF), particularly in the setting of coexisting conditions that affect coagulation. Coronavirus disease 2019 (COVID-19) has been associated with a hypercoagulable state, which may contribute to thrombus formation even in patients on anticoagulation. We describe a patient with persistent AF and recent gastrointestinal and intracranial bleeding who was incidentally found to have COVID-19 infection and was diagnosed with a large LAA thrombus. This case highlights the complex interplay between infection, underlying cardiac arrhythmia, and bleeding risk, emphasizing the importance of early recognition and careful management of thromboembolic risk in high-risk patients.