# Lurking in Ambush: A Case Report of Probable Creutzfeldt-Jakob Disease From Rural Kerala, India

## TL;DR

This case report describes a probable instance of Creutzfeldt-Jakob disease in an elderly man from rural India, highlighting diagnostic challenges in low-resource settings.

## Contribution

The novelty lies in documenting a probable CJD case in rural India, emphasizing clinical vigilance in resource-limited areas.

## Key findings

- The patient exhibited rapidly progressive neurocognitive decline and myoclonus.
- MRI and EEG findings supported a probable diagnosis of sporadic CJD.
- The case underscores the importance of clinical evaluation in diagnosing rare neurological disorders in rural areas.

## Abstract

Creutzfeldt-Jakob disease (CJD) is a rare, rapidly progressive neurodegenerative disorder caused by prion proteins. This case report describes a probable instance of sporadic CJD in an elderly male from rural Kerala, India. The patient presented with rapidly evolving neurocognitive decline, myoclonus, and characteristic MRI and EEG findings. Despite limited resources, a probable diagnosis was established through clinical evaluation and supportive investigations. This case highlights the challenges of diagnosing rare neurological disorders in resource-constrained settings and underscores the importance of clinical vigilance in rural healthcare practice.