# Clear Cell Papulosis Associated With Multiple Developmental Abnormalities of the Skin

## TL;DR

This paper reports a rare skin condition in children linked to multiple developmental abnormalities.

## Contribution

The paper presents a novel case of clear cell papulosis associated with multiple developmental skin abnormalities.

## Key findings

- Clear cell papulosis was found in conjunction with a congenital sacral dermoid cyst and nevus of Ota.
- Additional abnormalities included presumed accessory breast tissue and congenital triangular alopecia.
- The case highlights a possible association between clear cell papulosis and multiple developmental skin anomalies.

## Abstract

Clear cell papulosis of the skin is a rare condition in children characterized by multiple small hypopigmented macules or flat papules, predominantly distributed in the pubic area and over the abdomen, chest, and axillae, along the milk lines, and by mucin- and cytokeratin 7-positive large clear cells within the epidermis. Associations of clear cell papulosis with other diseases or disorders have been rarely described. We present a case of clear cell papulosis associated with a congenital sacral dermoid cyst, nevus of Ota, presumed accessory breast tissue, thin and lightly pigmented hair, congenital triangular alopecia, and a posterior helical ear pit.