# Decompressive Craniectomy With Abdominal Bone Flap Preservation in Herpes Simplex Encephalitis: A Case Report

**Authors:** Elizabeth Blanco Espinosa, Idalberto Luis Fernandez Eng, Idania Maria Cruzata Matos, Javier Peña, Ricardo Marlon Saro Del Valle

PMC · DOI: 10.7759/cureus.95262 · Cureus · 2025-10-23

## TL;DR

A child with severe brain swelling from herpes simplex encephalitis was treated with a surgical procedure to relieve pressure, leading to a successful recovery.

## Contribution

The case demonstrates the effectiveness of preserving the bone flap in the abdomen during decompressive surgery for HSE.

## Key findings

- Decompressive hemicraniectomy with abdominal bone flap preservation controlled life-threatening intracranial pressure.
- The patient showed favorable neurological recovery and successful cranial reconstruction at three months.
- The technique minimized infection risk and maintained bone viability for later use.

## Abstract

Herpes simplex encephalitis (HSE) is a rare but severe condition that can lead to significant morbidity and mortality. Although antiviral therapy with acyclovir has improved outcomes, some patients develop complications such as focal hemorrhagic necrosis and edema in the temporal lobe, with subsequent elevation of intracranial pressure (ICP) and uncal herniation, necessitating surgical intervention. We report a pediatric case of HSE with life-threatening ICP refractory to sedation, osmotic therapy, and moderate hyperventilation. Despite aggressive treatment, the patient underwent a left-sided decompressive hemicraniectomy, with the bone flap preserved in a subcutaneous abdominal pocket, a technique shown in previous studies to maintain bone viability and minimize infection risk. This approach effectively controlled ICP and allowed progressive neurological recovery. At three-month follow-ups, the patient demonstrated favorable neurological outcomes (Glasgow Outcome Scale = 5) with successful autologous cranial reconstruction.

## Linked entities

- **Chemicals:** acyclovir (PubChem CID 135398513)
- **Diseases:** Herpes simplex encephalitis (MONDO:0012521)

## Full-text entities

- **Diseases:** hyperventilation (MESH:D006985), uncal herniation (MESH:D004677), HSE (MESH:D020803), infection (MESH:D007239), hemorrhagic necrosis (MESH:D006470), edema (MESH:D004487)
- **Chemicals:** acyclovir (MESH:D000212)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12640269/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12640269/full.md

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Source: https://tomesphere.com/paper/PMC12640269